Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

Bibliographic Details
Title: Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis
Authors: Yongmei Liu, Lindsay M. Reynolds, Jingzhong Ding, Li Hou, Kurt Lohman, Tracey Young, Wei Cui, Zhiqing Huang, Carole Grenier, Ma Wan, Hendrik G. Stunnenberg, David Siscovick, Lifang Hou, Bruce M. Psaty, Stephen S. Rich, Jerome I. Rotter, Joel D. Kaufman, Gregory L. Burke, Susan Murphy, David R. Jacobs, Wendy Post, Ina Hoeschele, Douglas A. Bell, David Herrington, John S. Parks, Russell P. Tracy, Charles E. McCall, James H. Stein
Source: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Publisher Information: Nature Portfolio, 2017.
Publication Year: 2017
Collection: LCC:Science
Subject Terms: Science
More Details: The molecular mechanisms mediating the impact of environmental factors in atherosclerosis are unclear. Here, the authors examine CD14+ blood monocyte’s transcriptome and epigenome signatures to find differential methylation and expression of ARID5B to be associated with human atherosclerosis.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-017-00517-4
Access URL: https://doaj.org/article/ac550ee42c704e9ea9413177742ac970
Accession Number: edsdoj.550ee42c704e9ea9413177742ac970
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-017-00517-4
Published in:Nature Communications
Language:English