Deep vein thrombosis prophylaxis in patients who undergo knee arthroscopy: a systematic review

Bibliographic Details
Title: Deep vein thrombosis prophylaxis in patients who undergo knee arthroscopy: a systematic review
Authors: Udit Dave, Emma G. Lewis, Victoria K. Ierulli, Shreya M. Saraf, Mary K. Mulcahey
Source: Knee Surgery & Related Research, Vol 36, Iss 1, Pp 1-10 (2024)
Publisher Information: BMC, 2024.
Publication Year: 2024
Collection: LCC:Orthopedic surgery
Subject Terms: Deep vein thrombosis, Venous thromboembolism, DVT prophylaxis, Factor Xa inhibitor, Aspirin, Knee arthroscopy, Orthopedic surgery, RD701-811
More Details: Abstract Background Knee arthroscopy is one of the most common procedures performed by orthopedic surgeons. A potentially life-threatening complication following this procedure is deep vein thrombosis (DVT). DVT prophylaxis can be obtained both mechanically (e.g., compression stockings) and chemically (e.g., aspirin, anticoagulants, and factor Xa inhibitors). Currently, there is no standardized guideline for DVT prophylaxis following knee arthroscopy. The purpose of this systematic review was to summarize how DVT prophylaxis is employed for patients who undergo knee arthroscopy. Methods PubMed, Embase, and Cochrane Library were searched for studies published after 1998 according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies were included if they evaluated DVT prophylaxis regimens in patients of any age who underwent knee arthroscopy. Studies not written in English, that analyzed animals or cadavers, that did not directly evaluate patients undergoing knee arthroscopy, or that did not address DVT prophylaxis were excluded. Results The initial search identified 300 studies, 15 of which were included. These 15 studies examined methods of DVT prophylaxis, including compression stockings (2 of 18; 11%), aspirin (1 of 18; 6%), factor Xa inhibitors (2 of 18; 11%), low-molecular-weight heparin (12 of 18; 67%), and neuromuscular electrical stimulation (1 of 18; 6%). Overall, 7 of 15 (47%) studies recommended DVT prophylaxis in all patients, and 3 (20%) studies supported its use for high-risk patients. Five (33%) studies did not support DVT prophylaxis, citing low incidence of postoperative DVT. Conclusions Compression stockings, aspirin, factor Xa inhibitors, and low-molecular-weight heparin (LMWH) were identified as possible options for DVT prophylaxis in patients undergoing knee arthroscopy. For high-risk knee arthroscopy patients, factor Xa inhibitors and LMWH drugs are appropriate for DVT prophylaxis. Level of evidence Level III, systematic review of level I–III studies.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2234-2451
Relation: https://doaj.org/toc/2234-2451
DOI: 10.1186/s43019-024-00250-5
Access URL: https://doaj.org/article/54b7617f7cc04d97867a7e41fa556567
Accession Number: edsdoj.54b7617f7cc04d97867a7e41fa556567
Database: Directory of Open Access Journals
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More Details
ISSN:22342451
DOI:10.1186/s43019-024-00250-5
Published in:Knee Surgery & Related Research
Language:English