Bibliographic Details
| Title: |
Association of point‐of‐care testing for sST2 with clinical outcomes in patients hospitalized with heart failure |
| Authors: |
Yuyi Chen, Jingyuan Guan, Chen Qi, Yihang Wu, Jing Wang, Xuemei Zhao, Xinqing Li, Chunhui He, Jian Zhang, Yuhui Zhang |
| Source: |
ESC Heart Failure, Vol 11, Iss 5, Pp 2857-2868 (2024) |
| Publisher Information: |
Wiley, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
heart failure, sST2, point‐of‐care testing, prognosis, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: |
Abstract Aims This study aimed to investigate the association of soluble suppression of tumorigenicity‐2 (sST2) measured by point‐of‐care testing assay with clinical outcomes in patients hospitalized with heart failure after adjusting for other predictors including N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) and high‐sensitivity cardiac troponin T (hs‐cTnT). Methods A total of 1726 consecutive patients hospitalized with heart failure from July 2015 to December 2021 were enrolled. Baseline serum sST2 concentrations were measured by immunofluorescence assay. Primary endpoint event was the composite of all‐cause death, heart transplantation, or left ventricular assist device. Results During the median follow‐up duration of 682 days, 434 patients (25.1%) suffered from primary endpoint events. Baseline sST2 remained an independent predictor of the primary endpoint event in patients hospitalized with heart failure after adjusting for other predictors including NT‐proBNP and hs‐cTnT [per log (unit) increase, adjusted hazard ratio (HR) (95% confidence interval) (CI): 1.20 (1.09, 1.32), P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2055-5822 |
| Relation: |
https://doaj.org/toc/2055-5822 |
| DOI: |
10.1002/ehf2.14860 |
| Access URL: |
https://doaj.org/article/d53f1b96b0c44c45b7c99733086d43e4 |
| Accession Number: |
edsdoj.53f1b96b0c44c45b7c99733086d43e4 |
| Database: |
Directory of Open Access Journals |
