Bibliographic Details
| Title: |
Preclinical translational research and application of tumor organoids |
| Authors: |
XIA Yujia, YANG Zhenli, LIU Yuqin |
| Source: |
Jichu yixue yu linchuang, Vol 44, Iss 9, Pp 1214-1218 (2024) |
| Publisher Information: |
Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College., 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Medicine |
| Subject Terms: |
tumor organoid, precise treatment, organoid biobank, Medicine |
| More Details: |
More and more in-depth tumor mechanism research and clinical precision treatment have put forward higher requirements for the technology for the establishment of tumor models.More and more tumor organoids have been applied. This model is able to reproduce the genomic, transcriptome, proteome and other omics features of parental tumors without heterogeneity found in cell line models. Based on these characteristics, tumor organoids have gradually become a representative preclinical model, facilitating the translation of new research results and precision treatment of patients. This article summarizes the latest progress of tumor organoids on R&D of technology and application, focusing on the current methods of establishing tumor organoids, opportunities and challenges in clinical and research application. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
Chinese |
| ISSN: |
1001-6325 |
| Relation: |
http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-9-1214.pdf; https://doaj.org/toc/1001-6325 |
| DOI: |
10.16352/j.issn.1001-6325.2024.09.1214 |
| Access URL: |
https://doaj.org/article/53e531b73a5d4618addfb1c4def6ea2e |
| Accession Number: |
edsdoj.53e531b73a5d4618addfb1c4def6ea2e |
| Database: |
Directory of Open Access Journals |
