Bibliographic Details
| Title: |
A Testing Campaign Intervention Consisting of Peer-Facilitated Engagement, Point-of-Care HCV RNA Testing, and Linkage to Nursing Support to Enhance Hepatitis C Treatment Uptake among People Who Inject Drugs: The ETHOS Engage Study |
| Authors: |
Anna Conway, Heather Valerio, Maryam Alavi, David Silk, Carla Treloar, Behzad Hajarizadeh, Alison D. Marshall, Marianne Martinello, Andrew Milat, Adrian Dunlop, Carolyn Murray, Bianca Prain, Charles Henderson, Janaki Amin, Phillip Read, Pip Marks, Louisa Degenhardt, Jeremy Hayllar, David Reid, Carla Gorton, Thao Lam, Michael Christmass, Alexandra Wade, Mark Montebello, Gregory J. Dore, Jason Grebely |
| Source: |
Viruses, Vol 14, Iss 7, p 1555 (2022) |
| Publisher Information: |
MDPI AG, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Microbiology |
| Subject Terms: |
direct-acting antiviral era, Hepatitis C virus elimination, Hepatitis C virus infection, Hepatitis C virus treatment, people who inject drugs, Microbiology, QR1-502 |
| More Details: |
This study evaluated HCV treatment initiation among people who inject drugs (PWID) following an intervention of campaign days involving peer connection, point-of-care HCV RNA testing, and linkage to nursing support. ETHOS Engage is an observational cohort study of PWID attending 25 drug treatment clinics and needle and syringe programs in Australia (May 2018–September 2019). Point-of-care results were provided to the nurse, facilitating confirmatory testing and treatment. The study aimed to evaluate treatment uptake and factors associated with treatment at 24 months post-enrolment. There were 317 people with current HCV infection and eligible for treatment (median age 43, 65% male, 15% homeless, 69% receiving opioid agonist treatment, 70% injected in last month). Overall, 15% (47/317), 27% (85/317), 38% (120/317), and 49% (155/317) of people with current HCV infection had initiated treatment at 3-, 6-, 12-, and 24-months following testing, respectively. Homelessness (adjusted hazard ratio (aHR): 0.40; 95% confidence interval: 0.23, 0.71) and incarceration in the past 12 months (vs. never, aHR:0.46; 0.28, 0.76) were associated with decreased treatment initiation in the 24 months post-enrolment. This testing campaign intervention facilitated HCV treatment uptake among PWID. Further interventions are needed to achieve HCV elimination among people experiencing homelessness or incarceration. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1999-4915 |
| Relation: |
https://www.mdpi.com/1999-4915/14/7/1555; https://doaj.org/toc/1999-4915 |
| DOI: |
10.3390/v14071555 |
| Access URL: |
https://doaj.org/article/5376e33ad95145ac851503e0d894cfdc |
| Accession Number: |
edsdoj.5376e33ad95145ac851503e0d894cfdc |
| Database: |
Directory of Open Access Journals |
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