Impact of image guided fine needle aspiration cytology in diagnosis of pediatric hepatic mass and cytohistologic concordance

Bibliographic Details
Title: Impact of image guided fine needle aspiration cytology in diagnosis of pediatric hepatic mass and cytohistologic concordance
Authors: Chhanda Das, Madhumita Mukhopadhyay, Moumita Sengupta, Ashis Kumar Saha, Biswanath Mukhopadhyay
Source: Journal of Indian Association of Pediatric Surgeons, Vol 19, Iss 2, Pp 90-95 (2014)
Publisher Information: Wolters Kluwer Medknow Publications, 2014.
Publication Year: 2014
Collection: LCC:Pediatrics
LCC:Surgery
Subject Terms: Histopathology, pediatric hepatic mass, percutaneous fine needle aspiration cytology, Pediatrics, RJ1-570, Surgery, RD1-811
More Details: Background: Pediatric hepatic mass is a heterogeneous group of benign and malignant lesions. Percutaneous fine needle aspiration cytology (FNAC) can be utilized as a diagnostic modality to assess the nature of radiologically demonstrated hepatic lesions and thus facilitate individualized treatment. Aims and Objective: The objective of the present study was to determine the diagnostic accuracy of percutaneous FNAC of pediatric liver masses, a procedure that is less invasive than open biopsy. Materials and Methods: A prospective, observational study was carried out in the Department of Pathology in collaboration with Department of Pediatric surgery and Radio-diagnosis including 31 pediatric patients presenting over last two years (June 2011 to May 2013) with focal hepatic lesion on ultrasound and computed tomography (CT) scan. FNAC was carried out under image guidance and cytodiagnosis was reached after appropriate staining. By comparing with histopathology reports, diagnostic accuracy of cytology was evaluated. Result: Among 31 cases included in the study, 51.6% cases were cytologically benign and hemangioma was the most common benign lesion. Hepatoblastoma was the most accounted malignant tumour (12.9%). FNAC provided 94% sensitivity and 92% specificity in diagnosing benign and malignant tumours. Overall diagnostic accuracy was 93.10%. No significant complication was noted. Conclusion: Percutaneous FNAC under image guidance is an effective diagnostic tool for diagnosis of primary and metastatic tumours of liver in pediatric patients.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 0971-9261
1998-3891
Relation: http://www.jiaps.com/article.asp?issn=0971-9261;year=2014;volume=19;issue=2;spage=90;epage=95;aulast=Das; https://doaj.org/toc/0971-9261; https://doaj.org/toc/1998-3891
DOI: 10.4103/0971-9261.129602
Access URL: https://doaj.org/article/52bf68bb880b4a7a893ffc95add73d9d
Accession Number: edsdoj.52bf68bb880b4a7a893ffc95add73d9d
Database: Directory of Open Access Journals
More Details
ISSN:09719261
19983891
DOI:10.4103/0971-9261.129602
Published in:Journal of Indian Association of Pediatric Surgeons
Language:English