Personalized Surgical Management Offers Full Restitution and Unimpaired Quality of Life to Patients with Duplex Kidneys and Associated Pathologies: 30-year Follow-up at a Tertiary Referral Center

Bibliographic Details
Title: Personalized Surgical Management Offers Full Restitution and Unimpaired Quality of Life to Patients with Duplex Kidneys and Associated Pathologies: 30-year Follow-up at a Tertiary Referral Center
Authors: Lidija Ujkic, Karsten Haeffner, Friederike Praus, Martin Pohl, Philippe-Fabian Pohlmann, Malte Kroenig, Alexander Frankenschmidt, Christian Gratzke, Martin Schoenthaler
Source: European Urology Open Science, Vol 57, Iss , Pp 106-112 (2023)
Publisher Information: Elsevier, 2023.
Publication Year: 2023
Collection: LCC:Diseases of the genitourinary system. Urology
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Subject Terms: Duplex kidney, Ureterocele, Ectopic ureter, Heminephrectomy, Ureterocystic reimplantation, Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
More Details: Background: Duplex kidneys may be associated with additional pathologies with an indication for surgery. Various surgical approaches have been described. However, little is known about long-term outcomes and quality of life (QoL) for these patients. Objective: To present long-term outcomes and QoL data up to 30 yr after surgical treatment of duplex kidneys and associated pathologies. Design, setting, and participants: We collected clinical and operative data for all patients who underwent surgery for complicated duplex kidney at our institution from 1990 to 2018. All patients were invited for a follow-up examination or telephone interview. Outcome measurements and statistical analysis: We evaluated renal function, clinical outcomes, residual dilation of the upper urinary tract, and health-related QoL. Results and limitations: Of the 176 patients included, 173 were available for follow-up (mean 140.5 mo). Surgical treatment involved an upper-tract, lower-tract, or combined approach in 11%, 56%, and 33% of cases, respectively. Rates of perioperative complications (8%) and secondary surgery (10%) were low. Overall, 95% of our patients achieved full restitution. Renal function was preserved in all cases, with recurrent urinary tract infections reported by just 2% and urinary incontinence by 1%. Good health-related QoL was reported by 98% of patients. Those without full restitution included six patients who underwent total nephrectomy and two boys who underwent multiple surgeries and urinary diversion. Our results are limited by their retrospective nature, including partly incomplete data sets. Conclusions: Management of duplex kidneys and associated pathologies is complex and highly individual. By planning a personal approach for each patient it is possible to achieve full bodily integrity and good QoL for most of these patients. Patient summary: Almost all patients undergoing surgery for duplex kidneys and associated pathologies will lead a life without body impairment and good quality of life.This trial is registered in the German Clinical Trials Register as DRKS00022542.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2666-1683
Relation: http://www.sciencedirect.com/science/article/pii/S2666168323012892; https://doaj.org/toc/2666-1683
DOI: 10.1016/j.euros.2023.09.012
Access URL: https://doaj.org/article/c5245457ebb3421a996ec4e61c6e23d9
Accession Number: edsdoj.5245457ebb3421a996ec4e61c6e23d9
Database: Directory of Open Access Journals
More Details
ISSN:26661683
DOI:10.1016/j.euros.2023.09.012
Published in:European Urology Open Science
Language:English