Bibliographic Details
| Title: |
Systematic review and meta-analysis of vascular imaging features to predict outcome following intravenous rtPA for acute ischemic stroke |
| Authors: |
Ricardo C Nogueira, Edson eBor-Seng-Shu, Nazia eSaeed, Manoel Jacobsen Teixeira, Ronney ePanerai, Thompson G Robinson |
| Source: |
Frontiers in Neurology, Vol 7 (2016) |
| Publisher Information: |
Frontiers Media S.A., 2016. |
| Publication Year: |
2016 |
| Collection: |
LCC:Neurology. Diseases of the nervous system |
| Subject Terms: |
cerebral autoregulation, cerebral hemodynamics, clinical outcome, intracerebral haemorrhage, rtPA, Intracranial circulation, Neurology. Diseases of the nervous system, RC346-429 |
| More Details: |
Background: The present review investigated which findings in vascular imaging techniques can be used to predict clinical outcome and risk of symptomatic intracerebral haemorrhage (sICH) in patients who underwent intravenous thrombolytic treatment. Methods: Publications were searched and inclusion criteria were as follows: 1) published manuscripts, 2) patients with acute ischemic stroke managed with intravenous rtPA, and 3) availability of imaging assessment to determine vessel patency or regulation of cerebral blood flow prior to, during and/or after thrombolytic treatment. Clinical outcomes were divided into neurological outcome (NIHSS within 7 days) and functional outcome (modified Rankin score in 2 – 3 months). sICH was defined as rtPA-related intracerebral bleeding associated with any worsening of NIHSS. Results: Thirty-nine articles were selected. Recanalization was associated with improved neurological and functional outcome (OR=7.83; 95% CI, 3.71 – 16.53 and OR=11.12; 95% CI, 5.85 – 21.14; p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1664-2295 |
| Relation: |
http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00077/full; https://doaj.org/toc/1664-2295 |
| DOI: |
10.3389/fneur.2016.00077 |
| Access URL: |
https://doaj.org/article/520263caf37341a5abcaafd13d040461 |
| Accession Number: |
edsdoj.520263caf37341a5abcaafd13d040461 |
| Database: |
Directory of Open Access Journals |
