Academic Journal
A systematic review and meta-analysis of human biomonitoring studies on exposure to environmental pollutants in Iran
| Title: | A systematic review and meta-analysis of human biomonitoring studies on exposure to environmental pollutants in Iran |
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| Authors: | Mostafa Hadei, Abbas Shahsavani, Philip K. Hopke, Simin Naseri, Ahmadreza Yazdanbakhsh, Mohsen Sadani, Alireza Mesdaghinia, Maryam Yarahmadi, Masoumeh Rahmatinia, Sevda Fallah, Bahaaran Emam, Majid Kermani, Nemat Jaafarzadeh, Mohammadreza Alipour, Vajihe Hassanzadeh, Shahriyar Bazzazpour, Seyed Saeed Hashemi Nazari |
| Source: | Ecotoxicology and Environmental Safety, Vol 212, Iss , Pp 111986- (2021) |
| Publisher Information: | Elsevier, 2021. |
| Publication Year: | 2021 |
| Collection: | LCC:Environmental pollution LCC:Environmental sciences |
| Subject Terms: | Human biomonitoring, Biomarker, Heavy metals, Smoking, General population, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350 |
| More Details: | Population exposure to environmental contaminants can be precisely observed through human biomonitoring studies. The present study aimed to systematically review all the biomonitoring studies conducted in Iran on some selected carcinogen environmental pollutants. In this systematic review study, 11 carcinogen agents were selected including arsenic, cadmium, chromium, nickel, lindane, benzene, trichloroethylene (TCE), pentachlorophenol (PCP), radon-222, radium-224, − 226, − 228, and tobacco smoke. The Web of Science, PubMed, and Scopus databases were searched for peer-reviewed articles published in English. After several screening steps, data were extracted from the studies. Meta-analyses (a random-effect model using the DerSimonian-Laired method) were performed only for the biomarkers with more than three eligible articles, including cadmium in blood and breast milk, and arsenic in breast milk. Methodological quality of the studies was assessed using the Newcastle-Ottawa Quality Assessment Scale adapted for cross-sectional studies. Of the 610 articles found in the database search, 30 studies were eligible for qualitative review, and 13 were included in the meta-analysis (cadmium in blood (n = 3), cadmium in breast milk (n = 6), and arsenic in breast milk (n = 4)). The overall pooled average concentrations (95% CI) of cadmium in blood, cadmium in breast milk, and arsenic in breast milk were 0.11 (95% CI: 0.08, 0.14), 5.38 (95% CI: 3.60, 6.96), and 1.42 (95% CI: 1.02, 1.81) µg/L, respectively. These values were compared with the biomarker concentrations in other countries and health-based guideline values. This study showed that there is a need for comprehensive action plans to reduce the exposure of general population to these environmental contaminants. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 0147-6513 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S014765132100097X; https://doaj.org/toc/0147-6513 |
| DOI: | 10.1016/j.ecoenv.2021.111986 |
| Access URL: | https://doaj.org/article/519de420627b44ae9f22639c52aee268 |
| Accession Number: | edsdoj.519de420627b44ae9f22639c52aee268 |
| Database: | Directory of Open Access Journals |
| ISSN: | 01476513 |
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| DOI: | 10.1016/j.ecoenv.2021.111986 |
| Published in: | Ecotoxicology and Environmental Safety |
| Language: | English |