Bibliographic Details
| Title: |
Maternal Death by COVID-19 Associated with Elevated Troponin T Levels |
| Authors: |
Johnatan Torres-Torres, Raigam Jafet Martinez-Portilla, Salvador Espino y Sosa, Juan Mario Solis-Paredes, Jose Antonio Hernández-Pacheco, Paloma Mateu-Rogell, Anette Cravioto-Sapien, Adolfo Zamora-Madrazo, Guadalupe Estrada-Gutierrez, Miguel Angel Nares-Torices, Norma Patricia Becerra-Navarro, Virginia Medina-Jimenez, Jose Rafael Villafan-Bernal, Lourdes Rojas-Zepeda, Diana Hipolita Loya-Diaz, Manuel Casillas-Barrera |
| Source: |
Viruses, Vol 14, Iss 2, p 271 (2022) |
| Publisher Information: |
MDPI AG, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Microbiology |
| Subject Terms: |
COVID-19, maternal death, troponin T, Microbiology, QR1-502 |
| More Details: |
Cardiomyocyte injury and troponin T elevation has been reported within COVID-19 patients and are associated with a worse prognosis. Limited data report this association among COVID-19 pregnant patients. Objective: We aimed to analyze the association between troponin T levels in severe COVID-19 pregnant women and risk of viral sepsis, intensive care unit (ICU) admission, or maternal death. Methods: We performed a prospective cohort of all obstetrics emergency admissions from a Mexican National Institute. All pregnant women diagnosed by reverse transcription-polymerase chain reaction (RT-qPCR) for SARS-CoV-2 infection between October 2020 and May 2021 were included. Clinical data were collected, and routine blood samples were obtained at hospital admission. Seric troponin T was measured at admission. Results: From 87 included patients, 31 (35.63%) had severe COVID-19 pneumonia, and 6 (6.89%) maternal deaths. ROC showed a significant relationship between troponin T and maternal death (AUC 0.979, CI 0.500–1.000). At a cutoff point of 7 ng/mL the detection rate for severe pneumonia was 83.3% (95%CI: 0.500–0.100) at 10% false-positive rate. Conclusion: COVID-19 pregnant women with elevated levels of troponin T present a higher risk of death and severe pneumonia. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1999-4915 |
| Relation: |
https://www.mdpi.com/1999-4915/14/2/271; https://doaj.org/toc/1999-4915 |
| DOI: |
10.3390/v14020271 |
| Access URL: |
https://doaj.org/article/512fa0ad473f419cade2eeb095d6a165 |
| Accession Number: |
edsdoj.512fa0ad473f419cade2eeb095d6a165 |
| Database: |
Directory of Open Access Journals |
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