Bibliographic Details
| Title: |
Advanced technology for assessment of endoscopic and histological activity in ulcerative colitis: a systematic review and meta-analysis |
| Authors: |
Olga Maria Nardone, Yifat Snir, James Hodson, Rosanna Cannatelli, Nunzia Labarile, Keith Siau, Cesare Hassan, Henit Yanai, Iris Dotan, Subrata Ghosh, Marietta Iacucci |
| Source: |
Therapeutic Advances in Gastroenterology, Vol 15 (2022) |
| Publisher Information: |
SAGE Publishing, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Diseases of the digestive system. Gastroenterology |
| Subject Terms: |
Diseases of the digestive system. Gastroenterology, RC799-869 |
| More Details: |
Background: Advanced endoscopic technologies led to significant progress in the definition of endoscopic remission of ulcerative colitis (UC) and correlate better with histological changes, compared with standard endoscopy. However, while studies have assessed the diagnostic accuracy of endoscope technologies individually, there are currently limited data comparing between technologies. As such, the aim of this systematic review was to pool data from the existing literature and compare the correlations between endoscopy and histologic disease activity scores across endoscope technologies. Methods: We searched PubMed and Embase until February 2021 for eligible studies reporting the correlation between endoscopy and histology activity scores in UC. Studies were grouped by endoscope technology as standard-definition white light (SD-WLE), high-definition white light (HD-WLE) or electronic virtual chromoendoscopy (VCE) and comparisons made between these groups. Results: A total of N = 27 studies were identified, of which N = 12 were included in a meta-analysis of correlations between endoscopic and histological activity scores. Combining these studies identified considerable heterogeneity ( I 2 : 89–93%) and returned a pooled correlation coefficient ( ρ ) for the SD-WLE group of 0.74, which did not differ significantly from HD-WLE ( ρ : 0.65, p = 0.521) or VCE ( ρ : 0.70, p = 0.801). In addition, N = 4 studies reported the accuracy of endoscopic activity scores on WLE and VCE to diagnose histological remission. Pooling these found significantly higher accuracy for VCE, compared with WLE [risk ratio: 1.13, 95% confidence interval (CI): 1.07–1.19, p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1756-2848
17562848 |
| Relation: |
https://doaj.org/toc/1756-2848 |
| DOI: |
10.1177/17562848221092594 |
| Access URL: |
https://doaj.org/article/505cd0f67dc94be9b1b591db0522ee54 |
| Accession Number: |
edsdoj.505cd0f67dc94be9b1b591db0522ee54 |
| Database: |
Directory of Open Access Journals |
