Bibliographic Details
| Title: |
Mature T-Cell leukemias: Challenges in Diagnosis |
| Authors: |
Dima El-Sharkawi, Ayoma Attygalle, Claire Dearden |
| Source: |
Frontiers in Oncology, Vol 12 (2022) |
| Publisher Information: |
Frontiers Media S.A., 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
diagnostics, mature T and NK-cell neoplasms, T-PLL, T-cell prolymphocytic leukemia, large granular lymphocyte (LGL) leukemia, adult T-cell leukemia/lymphoma (ATL), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
T-cell clones can frequently be identified in peripheral blood. It can be difficult to appreciate whether these are benign and transient or whether they signify a clonal disorder. We review factors that aid in understanding the relevance of T-cell clones. Conversely, obvious pathological T-cell clones can be detected in blood, but there is uncertainty in how to categorize this clonal T cell population, thus, we adopt a multidisciplinary review of the clinical features, diagnostic material and radiology before making the diagnosis. In this review we shall discuss some of these challenges faced when diagnosing mature T-cell leukemias. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2234-943X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fonc.2022.777066/full; https://doaj.org/toc/2234-943X |
| DOI: |
10.3389/fonc.2022.777066 |
| Access URL: |
https://doaj.org/article/d50362b1ebcd432687ab1fa174df8c69 |
| Accession Number: |
edsdoj.50362b1ebcd432687ab1fa174df8c69 |
| Database: |
Directory of Open Access Journals |
