Variations in Lipid Profile During Critical Illness

Bibliographic Details
Title:	Variations in Lipid Profile During Critical Illness
Authors:	Mehreen Hassan, Tariq Bin Sharif, Aamir Ijaz, Naveed Asif, Azooba Fatima, Afshan Bibi
Source:	Pakistan Armed Forces Medical Journal, Vol 72, Iss 5 (2022)
Publisher Information:	Army Medical College Rawalpindi, 2022.
Publication Year:	2022
Collection:	LCC:Medicine LCC:Medicine (General)
Subject Terms:	Critical illness, High-Density Lipoprotein Cholesterol (HDL-C), Lipemia of sepsis Total cholesterol (TC), Lowdensity lipoprotein (LDL-C) Triglyceride (TG), Medicine, Medicine (General), R5-920
More Details:	Objective: To determine to mean change in levels of Triglycerides (TG), Total cholesterol (TC), High-Density Lipoprotein Cholesterol (HDL-C), and low-density lipoprotein (LDL-C) in critically ill patients at admission,18 hours and 42 hours after admission. Study Design: Cross-sectional study Place and Duration of Study: Department of Chemical Pathology & Endocrinology, Armed Forces Institute of Pathology Rawalpindi (AFIP), in collaboration with Military Hospital Rawalpindi (MH), Combined Military Hospital Rawalpindi (CMH) and Armed Forces Institute of Cardiology Rawalpindi (AFIC) Pakistan, from Mar to Sep 2016. Methodology: A total of Fifty patients admitted to intensive care units of MH, CMH and AFIC for coronary artery disease(CAD), sepsis, burns and cancer were included in the study. Patients on lipid-lowering drugs and post-surgery patients were excluded.TC, HDL-C, LDL-C and TG were analysed on ADVIA 1800 (SIEMENS, Germany). Results: Fifty patients were included with mean age of 48.12±2.26 years. Parametric analyses revealed significant increase in serum TG levels during hospitalization in critically ill patients in various disease groups (Mean±SD at admission, 18 hours and 42 hours): TG (CNS disorders 1.35±0.18, 1.78±0.24 and 1.22±0.17; CVS 1.92±0.21, 2.15±0.28 ,2.32 ±0.20; sepsis 1.55±0.18,1.38+0.24,1.54+0.17; malignancies 1.24±0.31, 1.28+0.42,1.35+0.30; renal disorders 1.39+0.35,1.82+0.47,1.08+0.33; (p
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	0030-9648 2411-8842
Relation:	https://www.pafmj.org/index.php/PAFMJ/article/view/9465; https://doaj.org/toc/0030-9648; https://doaj.org/toc/2411-8842
DOI:	10.51253/pafmj.v72i5.9465
Access URL:	https://doaj.org/article/4f27e96e3d3049568f79f8b86cd0260e
Accession Number:	edsdoj.4f27e96e3d3049568f79f8b86cd0260e
Database:	Directory of Open Access Journals
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More Details
ISSN:	00309648 24118842
DOI:	10.51253/pafmj.v72i5.9465
Published in:	Pakistan Armed Forces Medical Journal
Language:	English