Bibliographic Details
| Title: |
Neutrophil to lymphocyte ratio predicts early growth of traumatic intracerebral haemorrhage |
| Authors: |
Dongzhou Zhuang, Jiangtao Sheng, Guoyi Peng, Tian Li, Shirong Cai, Faxiu Din, Lianjie Li, Mindong Huang, Fei Tian, Kangsheng Li, Shousen Wang, Weiqiang Chen |
| Source: |
Annals of Clinical and Translational Neurology, Vol 8, Iss 8, Pp 1601-1609 (2021) |
| Publisher Information: |
Wiley, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
LCC:Neurology. Diseases of the nervous system |
| Subject Terms: |
Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429 |
| More Details: |
Abstract Objective The neutrophil to lymphocyte ratio (NLR) has been proposed to capture the inflammatory status of patients with various conditions involving the brain. This retrospective study aimed to explore the association between the NLR and the early growth of traumatic intracerebral haemorrhage (tICH) in patients with traumatic brain injury (TBI). Methods A multicentre, observational cohort study was conducted. Patients with cerebral contusion undergoing baseline computed tomography for haematoma volume analysis within 6 h after primary injury and follow‐up visits within 48 h were included. Routine blood tests were performed upon admission, and early growth of tICH was assessed. Prediction accuracies of the NLR for the early growth of tICH and subsequent surgical intervention in patients were analysed. Results There were a total of 1077 patients who met the criteria included in the study cohort. Univariate analysis results showed that multiple risk factors were associated with the early growth of tICH and included in the following multivariate analysis models. The multivariate logistic regression analysis results revealed that the NLR was highly associated with the early growth of tICH (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2328-9503 |
| Relation: |
https://doaj.org/toc/2328-9503 |
| DOI: |
10.1002/acn3.51409 |
| Access URL: |
https://doaj.org/article/4f251ac8d398440f9881bbb49ad2380b |
| Accession Number: |
edsdoj.4f251ac8d398440f9881bbb49ad2380b |
| Database: |
Directory of Open Access Journals |
