Clinical impact of magnetic resonance imaging distortions on gamma knife radiosurgery
| Title: | Clinical impact of magnetic resonance imaging distortions on gamma knife radiosurgery |
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| Authors: | Sinead Jacobson, Catherine Jones, Ryan Lusk, Mike Jenkins, Crispen Chamunyonga, Mark B Pinkham, Elizabeth Brown |
| Source: | Journal of Medical Radiation Sciences, Vol 68, Iss 3, Pp 274-281 (2021) |
| Publisher Information: | Wiley, 2021. |
| Publication Year: | 2021 |
| Collection: | LCC:Medical physics. Medical radiology. Nuclear medicine |
| Subject Terms: | Image distortion, Leksell Gamma Knife, magnetic resonance imaging, quality assurance, stereotactic radiosurgery, Medical physics. Medical radiology. Nuclear medicine, R895-920 |
| More Details: | Abstract Introduction Magnetic resonance imaging (MRI) is the preferred imaging modality for Leksell Gamma Knife® (LGK) stereotactic radiosurgery (SRS) treatment planning (TP) due to superior soft tissue definition compared to computed tomography (CT). However, inherent distortions in MRI can affect treatment accuracy. The aim of this study was to develop a model to visualise the effect of MRI distortion on LGK SRS target coverage. Methods A model was developed using MR images of a QUASARTM GRID3D QA phantom. One hundred and twenty‐five points were compared against known phantom geometry. Using linear interpolation, the model was applied retrospectively to 10 brain metastases patient data sets treated with LGK. The model estimated the corrected shot position accounting for distortion. A total of 44 metastases were investigated regarding the effects of MRI distortion on target coverage. Results The model indicated significantly reduced mean error by 0.30 mm and variance by 0.09 mm (P = 0.008). After model application, 23 (53%) metastases showed reduced coverage. Six of the 23 metastases were deemed to be potentially clinically significant changes. Results indicated MRI distortion had a greater effect on smaller targets (mean 0.06cc) located further away from the image isocentre (mean 64.88 mm). Conclusion This study developed a model to visualise the effect of MRI distortion on LGK SRS target coverage. Results suggest that MRI distortion can affect target coverage and the developed model may be one method to assess its impact. These results indicate that MRI distortion may have a greater effect on smaller targets located at the image periphery. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2051-3909 2051-3895 |
| Relation: | https://doaj.org/toc/2051-3895; https://doaj.org/toc/2051-3909 |
| DOI: | 10.1002/jmrs.472 |
| Access URL: | https://doaj.org/article/4ea30c2bdd314ebab71326697ba5a65c |
| Accession Number: | edsdoj.4ea30c2bdd314ebab71326697ba5a65c |
| Database: | Directory of Open Access Journals |
| ISSN: | 20513909 20513895 |
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| DOI: | 10.1002/jmrs.472 |
| Published in: | Journal of Medical Radiation Sciences |
| Language: | English |