Bone marrow metastasis in a patient with non‐seminomatous testicular germ cell tumor

Bibliographic Details
Title: Bone marrow metastasis in a patient with non‐seminomatous testicular germ cell tumor
Authors: Takashi Ueda, Ippei Takada, Teruki Shimizu, Saya Ito, Atsuko Fujihara, Takumi Shiraishi, Terukazu Nakamura, Osamu Ukimura
Source: IJU Case Reports, Vol 5, Iss 4, Pp 247-250 (2022)
Publisher Information: Wiley, 2022.
Publication Year: 2022
Collection: LCC:Diseases of the genitourinary system. Urology
Subject Terms: AFP, bone marrow metastasis, desperation RPLND, salvage chemotherapy, testicular germ cell tumor, Diseases of the genitourinary system. Urology, RC870-923
More Details: Introduction Metastasis to the bone marrow is rare in testicular germ cell tumor patients. We report a case of a patient with a non‐seminomatous testicular germ cell tumor who presented with bone marrow metastases after intensive chemotherapy. Case presentation A 36‐year‐old man was admitted to the hospital with pancytopenia. Previously, he had received intensive care for an advanced left testicular germ cell tumor. Although multidisciplinary treatments including several regimens of salvage chemotherapy, desperation retroperitoneal lymph node dissection, and focal radiotherapy were performed, the serum tumor marker alfa‐fetoprotein was not normalized and there were no findings of relapse by several imaging modalities. Bone marrow aspirate, conducted to diagnose a cause of pancytopenia, revealed metastatic germ cell tumors in the bone marrow. Conclusion Bone marrow metastasis should be considered as a differential diagnosis in patients with germ cell tumors whose serum tumor makers are not normalized without any radiographic finding of recurrence.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2577-171X
Relation: https://doaj.org/toc/2577-171X
DOI: 10.1002/iju5.12446
Access URL: https://doaj.org/article/4e443df3d39e469b84a0810847c257b9
Accession Number: edsdoj.4e443df3d39e469b84a0810847c257b9
Database: Directory of Open Access Journals
More Details
ISSN:2577171X
DOI:10.1002/iju5.12446
Published in:IJU Case Reports
Language:English