The course of gout in a patient with Cushing’s disease after successful surgical treatment
| Title: | The course of gout in a patient with Cushing’s disease after successful surgical treatment |
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| Authors: | L. K. Dzeranova, M. S. Eliseev, O. O. Golounina, E. V. Cheremushkina, E. A. Pigarova, G. A. Melnichenko |
| Source: | Ожирение и метаболизм, Vol 19, Iss 4, Pp 404-409 (2023) |
| Publisher Information: | Endocrinology Research Centre, 2023. |
| Publication Year: | 2023 |
| Collection: | LCC:Physiology LCC:Biochemistry |
| Subject Terms: | endogenous hypercortisolism, microcrystalline arthropathies, gout, arthritis, allopurinol, colchicine, clinical case, Physiology, QP1-981, Biochemistry, QD415-436 |
| More Details: | Endogenous hypercortisolism is a severe endocrine disease characterized by prolonged exposure to excessive amounts of glucocorticoid hormones, accompanied by a wide range of symptoms and complications, including immunosuppression. Timely surgical treatment in most cases allows to save the patient’s life, significantly improve its quality. However, restoration of the normal concentration of glucocorticoid hormones can become a trigger factor in the development or exacerbation of autoimmune and auto-inflammatory diseases. We present a clinical case of atypical gout in a patient with hypercortisolism and a progressive increase in symptoms of the disease after successful surgical treatment for Cushing’s disease and achieving stable remission. The issues of diagnosis and treatment of this group of autoinflammatory diseases are highlighted, the leading clinical and radiological symptoms are considered, the differential diagnosis of microcrystalline (metabolic) arthritis is presented. Despite the widespread, the diagnosis and treatment of this group of diseases still cause difficulties for specialists. A competent choice of drug therapy allows to fully control diseases considered in the article, including when they are combined, and thereby improve the quality of life of the patient. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English Russian |
| ISSN: | 2071-8713 2306-5524 |
| Relation: | https://www.omet-endojournals.ru/jour/article/view/12945; https://doaj.org/toc/2071-8713; https://doaj.org/toc/2306-5524 |
| DOI: | 10.14341/omet12945 |
| Access URL: | https://doaj.org/article/4d362b32cebd406f8e353e0aadb9ce2e |
| Accession Number: | edsdoj.4d362b32cebd406f8e353e0aadb9ce2e |
| Database: | Directory of Open Access Journals |
| ISSN: | 20718713 23065524 |
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| DOI: | 10.14341/omet12945 |
| Published in: | Ожирение и метаболизм |
| Language: | English Russian |