Bibliographic Details
Title: |
Polyfluorinated alcohol as a reusable media promoted catalyst-free green synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives |
Authors: |
Farzaneh Mohamadpour |
Source: |
Results in Chemistry, Vol 7, Iss , Pp 101546- (2024) |
Publisher Information: |
Elsevier, 2024. |
Publication Year: |
2024 |
Collection: |
LCC:Chemistry |
Subject Terms: |
Catalyst-free conditions, Polyfluorinated alcohol, Reusable promoting media, Green procedure, 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives, Chemistry, QD1-999 |
More Details: |
A green way to catalyst-free one-pot production of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives is described. It uses the Knoevenagel-Michael cyclic condensation method and polyfluorinated alcohol as a reusable promoting medium. This method follows the rules of green chemistry. Carrying out the reactions takes much less time while obtaining products with outstanding yields. This eco-friendly method uses safe reactions, doesn't need to be separated with column chromatography, is easy to produce and work-up, doesn't need a catalyst, is affordable and simple, and is cost-effective. Moreover, green 2,2,2-trifluoroethanol (TFE) is very stable and can be used again for 4 times without any major changes or loss of effectiveness. This makes it very useful for protecting the environment during industrial activities. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2211-7156 |
Relation: |
http://www.sciencedirect.com/science/article/pii/S221171562400242X; https://doaj.org/toc/2211-7156 |
DOI: |
10.1016/j.rechem.2024.101546 |
Access URL: |
https://doaj.org/article/4ce86b6b2478438d9540ff4c510a74cd |
Accession Number: |
edsdoj.4ce86b6b2478438d9540ff4c510a74cd |
Database: |
Directory of Open Access Journals |