Polyfluorinated alcohol as a reusable media promoted catalyst-free green synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives

Bibliographic Details
Title: Polyfluorinated alcohol as a reusable media promoted catalyst-free green synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives
Authors: Farzaneh Mohamadpour
Source: Results in Chemistry, Vol 7, Iss , Pp 101546- (2024)
Publisher Information: Elsevier, 2024.
Publication Year: 2024
Collection: LCC:Chemistry
Subject Terms: Catalyst-free conditions, Polyfluorinated alcohol, Reusable promoting media, Green procedure, 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives, Chemistry, QD1-999
More Details: A green way to catalyst-free one-pot production of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives is described. It uses the Knoevenagel-Michael cyclic condensation method and polyfluorinated alcohol as a reusable promoting medium. This method follows the rules of green chemistry. Carrying out the reactions takes much less time while obtaining products with outstanding yields. This eco-friendly method uses safe reactions, doesn't need to be separated with column chromatography, is easy to produce and work-up, doesn't need a catalyst, is affordable and simple, and is cost-effective. Moreover, green 2,2,2-trifluoroethanol (TFE) is very stable and can be used again for 4 times without any major changes or loss of effectiveness. This makes it very useful for protecting the environment during industrial activities.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2211-7156
Relation: http://www.sciencedirect.com/science/article/pii/S221171562400242X; https://doaj.org/toc/2211-7156
DOI: 10.1016/j.rechem.2024.101546
Access URL: https://doaj.org/article/4ce86b6b2478438d9540ff4c510a74cd
Accession Number: edsdoj.4ce86b6b2478438d9540ff4c510a74cd
Database: Directory of Open Access Journals
More Details
ISSN:22117156
DOI:10.1016/j.rechem.2024.101546
Published in:Results in Chemistry
Language:English