Increased adiponectin levels are associated with higher radiographic scores in the knee joint, but not in the hand joint

Bibliographic Details
Title: Increased adiponectin levels are associated with higher radiographic scores in the knee joint, but not in the hand joint
Authors: Haimuzi Xu, Ji-Hyoun Kang, Sung-Eun Choi, Dong-Jin Park, Sun-Seog Kweon, Young-Hoon Lee, Hye-Yeon Kim, Jung-Kil Lee, Min-Ho Shin, Shin-Seok Lee
Source: Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Publisher Information: Nature Portfolio, 2021.
Publication Year: 2021
Collection: LCC:Medicine
LCC:Science
Subject Terms: Medicine, Science
More Details: Abstract Several studies have evaluated the association between serum adiponectin levels and knee and hand osteoarthritis (OA); mixed results have been reported. We investigated the relationship between OA and serum adiponectin levels according to the radiographic features of knee and hand OA. A total of 2402 subjects was recruited from the Dong-gu Study. Baseline characteristics were collected via a questionnaire, and X-rays of knee and hand joints were scored using a semi-quantitative grading system. The relationship between serum adiponectin levels and radiographic severity was evaluated by linear and logistic regression analysis. Subjects in the higher serum adiponectin levels tertiles were older and had a lower body mass index (BMI) than those in the lower tertiles. Regarding knee joint scores, serum adiponectin levels was positively associated with the total (P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-021-81513-z
Access URL: https://doaj.org/article/4bfcd774ecad4ebeb063bb366c1b8f48
Accession Number: edsdoj.4bfcd774ecad4ebeb063bb366c1b8f48
Database: Directory of Open Access Journals
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More Details
ISSN:20452322
DOI:10.1038/s41598-021-81513-z
Published in:Scientific Reports
Language:English