Prognostic factors for survival in patients with metastatic lung adenocarcinoma: An analysis of the SEER database
| Title: | Prognostic factors for survival in patients with metastatic lung adenocarcinoma: An analysis of the SEER database |
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| Authors: | Begoña Campos‐Balea, Javier deCastro Carpeño, Bartomeu Massutí, David Vicente‐Baz, Diego Pérez Parente, Pedro Ruiz‐Gracia, Leonardo Crama, Manuel Cobo Dols |
| Source: | Thoracic Cancer, Vol 11, Iss 11, Pp 3357-3364 (2020) |
| Publisher Information: | Wiley, 2020. |
| Publication Year: | 2020 |
| Collection: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: | Lung adenocarcinoma, metastasis, non‐small cell lung cancer, overall survival, prognostic factor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: | Background Lung adenocarcinoma (ADC) is the main cause of death related to lung cancer. The aim of this study was to identify poor prognostic factors for overall survival (OS) in patients with stage IV lung ADC in real‐world clinical practice. Methods Patients were selected from the Surveillance Epidemiology and End Results (SEER) database. Chi‐square bivariate analysis was used for the association of binary qualitative variables. A multivariate Cox regression analysis was performed to determine the impact of these prognostic factors on OS. Results A total of 46 030 patients were included (51.3% men, mean age 67.03 ± 11.6), of whom 41.3% presented with metastases in bone, 28.9% in brain, 17.1% in liver and 31.8% in lung. Patients with liver metastases presented with two or more metastatic sites more frequently than patients without liver metastases (P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1759-7714 1759-7706 |
| Relation: | https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714 |
| DOI: | 10.1111/1759-7714.13681 |
| Access URL: | https://doaj.org/article/4bf6361d299944fa992649aabb369d44 |
| Accession Number: | edsdoj.4bf6361d299944fa992649aabb369d44 |
| Database: | Directory of Open Access Journals |
| ISSN: | 17597714 17597706 |
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| DOI: | 10.1111/1759-7714.13681 |
| Published in: | Thoracic Cancer |
| Language: | English |