Bibliographic Details
| Title: |
Accuracy of and preferences for blood-based versus oral-fluid-based HIV self-testing in Malawi: a cross-sectional study |
| Authors: |
Ailva O’Reilly, Webster Mavhu, Melissa Neuman, Moses K. Kumwenda, Cheryl C. Johnson, George Sinjani, Pitchaya Indravudh, Augustin Choko, Karin Hatzold, Elizabeth L. Corbett |
| Source: |
BMC Infectious Diseases, Vol 22, Iss S1, Pp 1-12 (2024) |
| Publisher Information: |
BMC, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Infectious and parasitic diseases |
| Subject Terms: |
HIV, Self-testing, Cross-sectional study, Malawi, Sub-Saharan Africa, Men, Infectious and parasitic diseases, RC109-216 |
| More Details: |
Abstract Background HIV self-testing (HIVST) can use either oral-fluid or blood-based tests. Studies have shown strong preferences for self-testing compared to facility-based services. Despite availability of low-cost blood-based HIVST options, to date, HIVST implementation in sub-Saharan Africa has largely been oral-fluid-based. We investigated whether users preferred blood-based (i.e. using blood sample derived from a finger prick) or oral fluid-based HIVST in rural and urban Malawi. Methods At clinics providing HIV testing services (n = 2 urban; n = 2 rural), participants completed a semi-structured questionnaire capturing sociodemographic data before choosing to test using oral-fluid-based HVST, blood-based HIVST or provider-delivered testing. They also completed a self-administered questionnaire afterwards, followed by a confirmatory test using the national algorithm then appropriate referral. We used simple and multivariable logistic regression to identify factors associated with preference for oral-fluid or blood-based HIVST. Results July to October 2018, N = 691 participants enrolled in this study. Given the choice, 98.4% (680/691) selected HIVST over provider-delivered testing. Of 680 opting for HIVST, 416 (61.2%) chose oral-fluid-based HIVST, 264 (38.8%) chose blood-based HIVST and 99.1% (674/680) reported their results appropriately. Self-testers who opted for blood-based HIVST were more likely to be male (50.3% men vs. 29.6% women, p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2334 |
| Relation: |
https://doaj.org/toc/1471-2334 |
| DOI: |
10.1186/s12879-024-09231-1 |
| Access URL: |
https://doaj.org/article/4ad925911cdb4245b0b2a4698c1c3ee6 |
| Accession Number: |
edsdoj.4ad925911cdb4245b0b2a4698c1c3ee6 |
| Database: |
Directory of Open Access Journals |
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