Timing and magnitude of regional right ventricular function and their relationship with early hospital mortality in patients with acute pulmonary embolism

Bibliographic Details
Title: Timing and magnitude of regional right ventricular function and their relationship with early hospital mortality in patients with acute pulmonary embolism
Authors: Batur Gönenç Kanar, Anıl Şahin, Gökhan Göl, Erhan Oğur, Murat Kavas, Halil Atas, Bülent Mutlu
Source: Anatolian Journal of Cardiology, Vol 22, Iss 1, Pp 26-32 (2019)
Publisher Information: KARE Publishing, 2019.
Publication Year: 2019
Collection: LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: pulmonary embolism, right ventricle, speckle-tracking echocardiography, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: Objective: Right ventricular (RV) dysfunction in acute pulmonary embolism (APE) has been associated with increased mortality and morbidity. The aim of the present study was to assess the timing and magnitude of regional RV functions using speckle-tracking echocardiography (STE) and their relationship to early hospital mortality in patients with APE. Methods: One hundred forty-two patients were prospectively studied at the onset of an acute episode and after a median follow-up period of 30 days. Their clinical and laboratory characteristics were recorded. For all patients, conventional two-dimensional echocardiography and STE were performed within 24 h after the diagnosis of APE. Results: Twenty-eight (19.7%) patients died during the hospitalization follow-up. Patients who died during hospitalization were older and had higher high sensitivity cardiac troponin T levels, and a higher percentage of patients had simplified Pulmonary Embolism Severity Indexes. In STE analyses, they had lower RV free wall peak longitudinal systolic strain (PLSS) and higher RV peak systolic strain dispersion indexes. The time to PLSS difference between RV free wall and LV lateral was longer in patients who died during hospitalization than in those who survived, and this was an independent predictor of early hospital mortality with 85.7% sensitivity and 75.0% specificity in patients with APE. Conclusion: APE was associated with RV electromechanical delay and dispersion. Electromechanical delay index might be useful to predict early hospital mortality in patients with APE.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2149-2263
Relation: https://jag.journalagent.com/z4/download_fulltext.asp?pdir=anatoljcardiol&un=AJC-38906; https://doaj.org/toc/2149-2263
DOI: 10.14744/AnatolJCardiol.2019.38906
Access URL: https://doaj.org/article/e49003558e194acb87c751ed8a69769a
Accession Number: edsdoj.49003558e194acb87c751ed8a69769a
Database: Directory of Open Access Journals
More Details
ISSN:21492263
DOI:10.14744/AnatolJCardiol.2019.38906
Published in:Anatolian Journal of Cardiology
Language:English