Eculizumab as a promising treatment in thymoma-associated myasthenia gravis

Bibliographic Details
Title: Eculizumab as a promising treatment in thymoma-associated myasthenia gravis
Authors: Valentina Vélez-Santamaría, Velina Nedkova, Laura Díez, Christian Homedes, M. Antonia Alberti, Carlos Casasnovas
Source: Therapeutic Advances in Neurological Disorders, Vol 13 (2020)
Publisher Information: SAGE Publishing, 2020.
Publication Year: 2020
Collection: LCC:Neurology. Diseases of the nervous system
Subject Terms: Neurology. Diseases of the nervous system, RC346-429
More Details: Myasthenia gravis is a chronic autoimmune disorder caused by antibodies directed against the neuromuscular junction. Some patients may have an associated thymoma, which confers a worse prognosis. Eculizumab, a monoclonal antibody that inhibits the activation of terminal complement, has recently been approved for the treatment of refractory generalized myasthenia gravis. This is an early case report of thymoma-associated refractory myasthenia gravis successfully treated with eculizumab in a real-world setting.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1756-2864
17562864
Relation: https://doaj.org/toc/1756-2864
DOI: 10.1177/1756286420932035
Access URL: https://doaj.org/article/48f75920ab2b4b8580922b56d5bacfbe
Accession Number: edsdoj.48f75920ab2b4b8580922b56d5bacfbe
Database: Directory of Open Access Journals
More Details
ISSN:17562864
DOI:10.1177/1756286420932035
Published in:Therapeutic Advances in Neurological Disorders
Language:English