The Botrytis cinerea Reg1 Protein, a Putative Transcriptional Regulator, Is Required for Pathogenicity, Conidiogenesis, and the Production of Secondary Metabolites
| Title: | The Botrytis cinerea Reg1 Protein, a Putative Transcriptional Regulator, Is Required for Pathogenicity, Conidiogenesis, and the Production of Secondary Metabolites |
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| Authors: | Caroline B. Michielse, Matthias Becker, Jens Heller, Javier Moraga, Isidro G. Collado, Paul Tudzynski |
| Source: | Molecular Plant-Microbe Interactions, Vol 24, Iss 9, Pp 1074-1085 (2011) |
| Publisher Information: | The American Phytopathological Society, 2011. |
| Publication Year: | 2011 |
| Collection: | LCC:Microbiology LCC:Botany |
| Subject Terms: | Microbiology, QR1-502, Botany, QK1-989 |
| More Details: | Botrytis cinerea, which causes gray-mold rot, attacks a wide range of plant species. To understand the infection process, the role of a putative transcriptional regulator, BcReg1 (regulator 1), in pathogenicity was studied. This transcriptional regulator shows similarity to the morphological switch regulators Candida albicans Wor1 and Histoplasma capsulatum Ryp1. Gene knock-out and complementation studies revealed that bcreg1 is required for pathogenicity. The bcreg1 mutant is able to penetrate plant tissue but is not able to cause necrotic lesions. In addition, the mutant is blocked in conidia formation and does not produce detectable levels of the sesquiterpene botrydial and the polyketide botcinic acid. Based on transcript expression levels, it can be concluded that bcreg1 is a downstream target of two mitogen-activated protein kinases, BcSak1 and Bmp3. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1943-7706 0894-0282 |
| Relation: | https://doaj.org/toc/0894-0282; https://doaj.org/toc/1943-7706 |
| DOI: | 10.1094/MPMI-01-11-0007 |
| Access URL: | https://doaj.org/article/a47f428762b4473b9d2a7e857f390e07 |
| Accession Number: | edsdoj.47f428762b4473b9d2a7e857f390e07 |
| Database: | Directory of Open Access Journals |
| ISSN: | 19437706 08940282 |
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| DOI: | 10.1094/MPMI-01-11-0007 |
| Published in: | Molecular Plant-Microbe Interactions |
| Language: | English |