The impact of recipient age on the effects of umbilical cord mesenchymal stem cells on HBV-related acute-on-chronic liver failure and liver cirrhosis

Bibliographic Details
Title:	The impact of recipient age on the effects of umbilical cord mesenchymal stem cells on HBV-related acute-on-chronic liver failure and liver cirrhosis
Authors:	Ka Zhang, Haixia Sun, Huijuan Cao, Yifan Jia, Xin Shu, Hong Cao, Yufeng Zhang, Xiaoan Yang
Source:	Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2021)
Publisher Information:	BMC, 2021.
Publication Year:	2021
Collection:	LCC:Medicine (General) LCC:Biochemistry
Subject Terms:	Umbilical cord mesenchymal stem cell transplantation, Liver failure, Liver cirrhosis, Hepatitis B virus, Age factors, Medicine (General), R5-920, Biochemistry, QD415-436
More Details:	Abstract Background The results of a previous study verified that umbilical cord mesenchymal stem cells (UCMSCs) have good therapeutic effects for the treatment of HBV-related acute-on-chronic liver failure (ACLF) and liver cirrhosis (LC). Nevertheless, it is still unknown whether the effects of UCMSCs are affected by recipient age. Methods Patients treated with UCMSCs who met the criteria of HBV-related ACLF and liver cirrhosis were identified in this retrospective observational study. Patients were divided into subgroups according to the World Health Organization (WHO) age criteria (
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	1757-6512
Relation:	https://doaj.org/toc/1757-6512
DOI:	10.1186/s13287-021-02544-x
Access URL:	https://doaj.org/article/47275d42085a4c62baab78040ccb9994
Accession Number:	edsdoj.47275d42085a4c62baab78040ccb9994
Database:	Directory of Open Access Journals
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More Details
ISSN:	17576512
DOI:	10.1186/s13287-021-02544-x
Published in:	Stem Cell Research & Therapy
Language:	English