Bibliographic Details
Title: |
Insulin Resistance Is Associated with Prevalence of Physician-Diagnosed Urinary Incontinence in Postmenopausal Non-Diabetic Adult Women: Data from the Fourth Korea National Health and Nutrition Examination Survey. |
Authors: |
Byung Il Yoon, Kyung-Do Han, Kyu Won Lee, Hyuk Sang Kwon, Sun Wook Kim, Dong Wan Sohn, Yong-Hyun Cho, U-Syn Ha |
Source: |
PLoS ONE, Vol 10, Iss 11, p e0141720 (2015) |
Publisher Information: |
Public Library of Science (PLoS), 2015. |
Publication Year: |
2015 |
Collection: |
LCC:Medicine LCC:Science |
Subject Terms: |
Medicine, Science |
More Details: |
To investigate the association between insulin resistance (IR) and urinary incontinence in Korean adult women by analyzing the data from the Korea National Health and Nutrition Examination Survey IV (KNHANES) 2007-2009.A nationally representative sample of 5318 non-diabetic Korean women ≥19-years-of-age (3043 premenopausal and 2275 postmenopausal women) was included from KNHANES 2008-2010. IR was measured using the homeostasis model assessment of IR (HOMA-IR). Participants in the highest and lowest quartile of HOMA-IR were defined as insulin-resistant and insulin-sensitive respectively. Women who have current physician-diagnosed urinary incontinence were classified as having urinary incontinence.Incontinence was found in 9.18% of the total population, 8.51% of the premenopausal population, and 10.86% of the postmenopausal population. The prevalence of incontinence increased with age, reaching a peak at 60-69-years-of-age. The prevalence of urinary incontinence increased significantly with higher HOMA-IR quartiles in pre- and post-menopausal women (p for linear association = 0.0458 and 0.0009 respectively). Among post-menopausal women, those in the highest quartile of HOMA-IR were significantly more likely to have urinary incontinence compared to those in the lowest quartile [adjusted odds ratio, 1.72; 95% confidence interval, 1.07-2.77]. However premenopausal population exhibited no association between incontinence and HOMA-IR quartiles.Our results suggest that the prevalence of incontinence increased across HOMA-IR in non-diabetic adult women, and especially, IR might be a risk factor for incontinence in postmenopausal non-diabetic women. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
1932-6203 |
Relation: |
http://europepmc.org/articles/PMC4631470?pdf=render; https://doaj.org/toc/1932-6203 |
DOI: |
10.1371/journal.pone.0141720 |
Access URL: |
https://doaj.org/article/e47007c985b442f7a1d4ae802159074f |
Accession Number: |
edsdoj.47007c985b442f7a1d4ae802159074f |
Database: |
Directory of Open Access Journals |