Bibliographic Details
| Title: |
A molecular atlas of innate immunity to adjuvanted and live attenuated vaccines, in mice |
| Authors: |
Audrey Lee, Madeleine K. D. Scott, Florian Wimmers, Prabhu S. Arunachalam, Wei Luo, Christopher B. Fox, Mark Tomai, Purvesh Khatri, Bali Pulendran |
| Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022) |
| Publisher Information: |
Nature Portfolio, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Adjuvants provide additional impetus for the immune response to vaccination regimens, however their modes of activity and impact on particular compartments of the immune response are currently not well understood. Here the authors perform high resolution assessment of the immune response to a well-established vaccination model and show innate immune transcriptomic and epigenomic alterations of innate cells in the lymph nodes following vaccination. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-022-28197-9 |
| Access URL: |
https://doaj.org/article/c4581bcc26564fe192f49148678f0969 |
| Accession Number: |
edsdoj.4581bcc26564fe192f49148678f0969 |
| Database: |
Directory of Open Access Journals |
