Bibliographic Details
| Title: |
Research advances in serum chitinase-3-like protein 1 in liver fibrosis |
| Authors: |
Xingwei Hu, Wenhan Liu, Jianhua Liu, Bojian Wang, Xiaosong Qin |
| Source: |
Frontiers in Medicine, Vol 11 (2024) |
| Publisher Information: |
Frontiers Media S.A., 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Medicine (General) |
| Subject Terms: |
biomarker, chitinase-3-like protein 1, liver fibrosis, non-alcoholic fatty liver disease, viral hepatitis, Medicine (General), R5-920 |
| More Details: |
While liver fibrosis remains a serious, progressive, chronic liver disease, and factors causing damage persist, liver fibrosis may develop into cirrhosis and liver cancer. However, short-term liver fibrosis is reversible. Therefore, an early diagnosis of liver fibrosis in the reversible transition phase is important for effective treatment of liver diseases. Chitinase-3-like protein 1 (CHI3L1), an inflammatory response factor that participates in various biological processes and is abundant in liver tissue, holds promise as a potential biomarker for liver diseases. Here, we aimed to review research developments regarding serum CHI3L1 in relation to the pathophysiology and diagnosis of liver fibrosis of various etiologies, providing a reference for the diagnosis, treatment, and prognosis of liver diseases. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2296-858X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fmed.2024.1372434/full; https://doaj.org/toc/2296-858X |
| DOI: |
10.3389/fmed.2024.1372434 |
| Access URL: |
https://doaj.org/article/452e6b80132547e4adb49849364fdd77 |
| Accession Number: |
edsdoj.452e6b80132547e4adb49849364fdd77 |
| Database: |
Directory of Open Access Journals |
