Bibliographic Details
| Title: |
Outcomes of COVID-19 in the Omicron-predominant wave: large-scale real-world data analysis with a comparison to influenza |
| Authors: |
Koichi Miyashita, Hironao Hozumi, Kazuki Furuhashi, Eiji Nakatani, Yusuke Inoue, Hideki Yasui, Yuzo Suzuki, Masato Karayama, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Toshiyuki Ojima, Takafumi Suda |
| Source: |
Pneumonia, Vol 17, Iss 1, Pp 1-12 (2025) |
| Publisher Information: |
BMC, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Diseases of the respiratory system |
| Subject Terms: |
COVID-19, Influenza, Mortality, National Database of Health Insurance Claims and Specific Health Checkups of Japan, NDB, Diseases of the respiratory system, RC705-779 |
| More Details: |
Abstract Purpose Studies on COVID-19 mortality during the Omicron-predominant wave have focused primarily on the inpatient/emergency room setting, and real-world data including both inpatients and outpatients are lacking. Methods Patients diagnosed with COVID-19 (n = 27,440,148) or influenza (n = 8,179,641) from January 2020 to April 2023 were identified using nationwide claims data in Japan. Patients with COVID-19 in the Omicron-predominant wave were compared with their counterparts in earlier waves, and a subset of the former group (May 2022–April 2023) was compared with patients with influenza as controls. Results The mortality rates (average number of deaths/cases per week) of COVID-19 decreased over time, being 2.7% (169/6312), 2.1% (397/18,754), 0.7% (195/28,273), and 0.4% (1613/378,848) in the wild-type–, Alpha-, Delta-, and Omicron-predominant waves, respectively. However, the number of deaths increased substantially in the Omicron-predominant wave, especially among the elderly (e.g., in the Delta- and Omicron-predominant waves, the average numbers of deaths/cases per week were |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2200-6133 |
| Relation: |
https://doaj.org/toc/2200-6133 |
| DOI: |
10.1186/s41479-025-00158-y |
| Access URL: |
https://doaj.org/article/44e80bf3fb7643cb9ef4db874b8e412a |
| Accession Number: |
edsdoj.44e80bf3fb7643cb9ef4db874b8e412a |
| Database: |
Directory of Open Access Journals |
