Title: |
Radiation therapy in functioning and no functioning pituitary neuroendocrine tumor: systematic review of the recent literature after 2011 |
Authors: |
Racha-Miloda Hemaidia, Hélène Cebula, Bernard Goichot, Georges Noel |
Source: |
Frontiers in Endocrinology, Vol 15 (2024) |
Publisher Information: |
Frontiers Media S.A., 2024. |
Publication Year: |
2024 |
Collection: |
LCC:Diseases of the endocrine glands. Clinical endocrinology |
Subject Terms: |
pituitary, adenoma, PiNET, radiotherapy highlights, radiation therapy, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
More Details: |
SummaryNeuroendocrine pituitary tumor, a benign cells proliferation, can cause significant morbidity due to its local invasiveness and secretory properties. Historically, radiotherapy has been employed as a second or third-line treatment option, with studies dating back to the mid-20th century. However, advancements in radiotherapy techniques, such as intensity-modulated radiation therapy (IMRT), stereotactic radiosurgery, and proton therapy, have revolutionized treatment approaches. This review aims to critically evaluate the recent literature (2011–2022) on the use of radiotherapy in both functioning and nonfunctioning neuroendocrine pituitary tumor. We employed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodology to systematically analyze 52 articles, focusing on local and hormonal control, radiotherapy protocols, and treatment-related side effects. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
1664-2392 |
Relation: |
https://www.frontiersin.org/articles/10.3389/fendo.2024.1468724/full; https://doaj.org/toc/1664-2392 |
DOI: |
10.3389/fendo.2024.1468724 |
Access URL: |
https://doaj.org/article/4429bcf9c4d34601bc161279f0b9c4eb |
Accession Number: |
edsdoj.4429bcf9c4d34601bc161279f0b9c4eb |
Database: |
Directory of Open Access Journals |