Bibliographic Details
Title: |
An immune response characterizes early Alzheimer’s disease pathology and subjective cognitive impairment in hydrocephalus biopsies |
Authors: |
Wenrui Huang, Anne Marie Bartosch, Harrison Xiao, Suvrajit Maji, Elliot H. H. Youth, Xena Flowers, Sandra Leskinen, Zeljko Tomljanovic, Gail Iodice, Deborah Boyett, Eleonora Spinazzi, Vilas Menon, Robert A. McGovern, Guy M. McKhann, Andrew F. Teich |
Source: |
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021) |
Publisher Information: |
Nature Portfolio, 2021. |
Publication Year: |
2021 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Specific transcriptional changes in microglia associated with Alzheimer’s disease have been reported. Here, the authors show that transcriptional analysis of human hydrocephalus biopsies identifies changes in immune response genes associated with early AD pathology, including cognitive decline. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-021-25902-y |
Access URL: |
https://doaj.org/article/43b5c7a214414bc4bb15263806a47f08 |
Accession Number: |
edsdoj.43b5c7a214414bc4bb15263806a47f08 |
Database: |
Directory of Open Access Journals |