An immune response characterizes early Alzheimer’s disease pathology and subjective cognitive impairment in hydrocephalus biopsies

Bibliographic Details
Title: An immune response characterizes early Alzheimer’s disease pathology and subjective cognitive impairment in hydrocephalus biopsies
Authors: Wenrui Huang, Anne Marie Bartosch, Harrison Xiao, Suvrajit Maji, Elliot H. H. Youth, Xena Flowers, Sandra Leskinen, Zeljko Tomljanovic, Gail Iodice, Deborah Boyett, Eleonora Spinazzi, Vilas Menon, Robert A. McGovern, Guy M. McKhann, Andrew F. Teich
Source: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Publisher Information: Nature Portfolio, 2021.
Publication Year: 2021
Collection: LCC:Science
Subject Terms: Science
More Details: Specific transcriptional changes in microglia associated with Alzheimer’s disease have been reported. Here, the authors show that transcriptional analysis of human hydrocephalus biopsies identifies changes in immune response genes associated with early AD pathology, including cognitive decline.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-021-25902-y
Access URL: https://doaj.org/article/43b5c7a214414bc4bb15263806a47f08
Accession Number: edsdoj.43b5c7a214414bc4bb15263806a47f08
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-021-25902-y
Published in:Nature Communications
Language:English