Association of triglyceride-glucose index and derived indices with cataract in middle-aged and elderly Americans: NHANES 2005–2008

Bibliographic Details
Title: Association of triglyceride-glucose index and derived indices with cataract in middle-aged and elderly Americans: NHANES 2005–2008
Authors: Bin Wei, Xin Hu, Ben-Liang Shu, Qin-Yi Huang, Hua Chai, Hao-Yu Yuan, Lin Zhou, Yi-Chong Duan, Li-Li Yao, Zhuo-Er Dong, Xiao-rong Wu
Source: Lipids in Health and Disease, Vol 24, Iss 1, Pp 1-11 (2025)
Publisher Information: BMC, 2025.
Publication Year: 2025
Collection: LCC:Nutritional diseases. Deficiency diseases
Subject Terms: TyG, Cataract, Metabolic syndrome, Nutritional diseases. Deficiency diseases, RC620-627
More Details: Abstract Aim Explore the relationship between the triglyceride-glucose (TyG) index, along with its derivative indices, and the prevalence of cataracts. Methods Data from 20,497 participants in the 2005–2008 National Health and Nutrition Examination Survey (NHANES) were compiled. A final total of 4,499 individuals met the eligibility criteria. Cataract presence was assessed through a self-reported history of cataract surgery. The TyG index and its derivatives—TyG-waist-to-height ratio (WHtR), TyG-neutrophil-to-lymphocyte ratio (NLR), TyG-monocyte-to-lymphocyte ratio (MLR), TyG-log platelet-to-lymphocyte ratio (lgPLR), TyG-log systemic inflammation index (lgSII), and TyG-systemic inflammation response index (SIRI)—were calculated. Statistical analyses included multivariable logistic regression, restricted cubic spline (RCS) curves for nonlinear relationships, and receiver operating characteristic (ROC) analysis. Results Higher TyG indices were significantly associated with cataract presence (P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1476-511X
Relation: https://doaj.org/toc/1476-511X
DOI: 10.1186/s12944-025-02470-4
Access URL: https://doaj.org/article/436bba0723f7470096eabd60744c3c9b
Accession Number: edsdoj.436bba0723f7470096eabd60744c3c9b
Database: Directory of Open Access Journals
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More Details
ISSN:1476511X
DOI:10.1186/s12944-025-02470-4
Published in:Lipids in Health and Disease
Language:English