Bibliographic Details
Title: |
Association of triglyceride-glucose index and derived indices with cataract in middle-aged and elderly Americans: NHANES 2005–2008 |
Authors: |
Bin Wei, Xin Hu, Ben-Liang Shu, Qin-Yi Huang, Hua Chai, Hao-Yu Yuan, Lin Zhou, Yi-Chong Duan, Li-Li Yao, Zhuo-Er Dong, Xiao-rong Wu |
Source: |
Lipids in Health and Disease, Vol 24, Iss 1, Pp 1-11 (2025) |
Publisher Information: |
BMC, 2025. |
Publication Year: |
2025 |
Collection: |
LCC:Nutritional diseases. Deficiency diseases |
Subject Terms: |
TyG, Cataract, Metabolic syndrome, Nutritional diseases. Deficiency diseases, RC620-627 |
More Details: |
Abstract Aim Explore the relationship between the triglyceride-glucose (TyG) index, along with its derivative indices, and the prevalence of cataracts. Methods Data from 20,497 participants in the 2005–2008 National Health and Nutrition Examination Survey (NHANES) were compiled. A final total of 4,499 individuals met the eligibility criteria. Cataract presence was assessed through a self-reported history of cataract surgery. The TyG index and its derivatives—TyG-waist-to-height ratio (WHtR), TyG-neutrophil-to-lymphocyte ratio (NLR), TyG-monocyte-to-lymphocyte ratio (MLR), TyG-log platelet-to-lymphocyte ratio (lgPLR), TyG-log systemic inflammation index (lgSII), and TyG-systemic inflammation response index (SIRI)—were calculated. Statistical analyses included multivariable logistic regression, restricted cubic spline (RCS) curves for nonlinear relationships, and receiver operating characteristic (ROC) analysis. Results Higher TyG indices were significantly associated with cataract presence (P |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
1476-511X |
Relation: |
https://doaj.org/toc/1476-511X |
DOI: |
10.1186/s12944-025-02470-4 |
Access URL: |
https://doaj.org/article/436bba0723f7470096eabd60744c3c9b |
Accession Number: |
edsdoj.436bba0723f7470096eabd60744c3c9b |
Database: |
Directory of Open Access Journals |
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