| Title: |
Comprehensive insights into tuberculosis-associated hemophagocytic lymphohistiocytosis: a systematic review |
| Authors: |
Arvin Eslami, Shaya Alimoghadam, Sanaz Khodadadi, Hadi Allahverdi, Rojina Alimoghadam, Amir Kasaeian, Davood Mansouri, Kamran Alimoghaddam, Ilad Alavi Darazam |
| Source: |
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-15 (2024) |
| Publisher Information: |
BMC, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Infectious and parasitic diseases |
| Subject Terms: |
Hemophagocytic lymphohistiocytosis, HLH, Tuberculosis, TB-HLH, Intravenous immunoglobulin, Infectious and parasitic diseases, RC109-216 |
| More Details: |
Abstract Background Tuberculosis-associated hemophagocytic lymphohistiocytosis (TB-HLH) presents significant challenges in diagnosis and treatment due to its complex interplay between TB and HLH. This systematic review aims to provide comprehensive insights into the epidemiology, clinical characteristics, and treatment outcomes of TB-HLH patients. Methods We performed a systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, searching PubMed, Scopus, Web of Science, and Embase up to May 16, 2023, without language restrictions. We included case reports and cases series on patients with both TB and HLH with documented treatment outcomes. Data were analyzed using descriptive statistics, chi-square or Fisher’s exact tests, t-tests, and mortality rates. Significant variables (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2334 |
| Relation: |
https://doaj.org/toc/1471-2334 |
| DOI: |
10.1186/s12879-024-10220-7 |
| Access URL: |
https://doaj.org/article/dde42c963dd840868a5db58b62a72b34 |
| Accession Number: |
edsdoj.42c963dd840868a5db58b62a72b34 |
| Database: |
Directory of Open Access Journals |
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