Bibliographic Details
| Title: |
Regio- and enantioselective umpolung gem-difluoroallylation of hydrazones via palladium catalysis enabled by N-heterocyclic carbene ligand |
| Authors: |
Shuai Huang, Fei-Fei Tong, Da-Chang Bai, Gao-Peng Zhang, Yang-Jie Jiang, Bo Zhang, Xuebing Leng, Ying-Long Guo, Xiao-Long Wan, Xingang Zhang, Chang-Hua Ding, Xue-Long Hou |
| Source: |
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021) |
| Publisher Information: |
Nature Portfolio, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Installation of difluoroalkyl groups while also imparting stereochemical information is mostly only possible with organocatalytic methods that activate carbonyls. Here the authors show a method to perform an difluoroallylation of hydrazones, forming a masked amine stereocenter, via palladium- and N-heterocyclic-carbene catalysis. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-021-26667-0 |
| Access URL: |
https://doaj.org/article/41a5e97b879a423fa0da4d0267aedd85 |
| Accession Number: |
edsdoj.41a5e97b879a423fa0da4d0267aedd85 |
| Database: |
Directory of Open Access Journals |
