Bibliographic Details
| Title: |
Amphilectene Diterpene Isonitriles and Formamido Derivatives from the Hainan Nudibranch Phyllidia Coelestis |
| Authors: |
Marianna Carbone, Maria Letizia Ciavatta, Emiliano Manzo, Xiao-Lu Li, Ernesto Mollo, I Wayan Mudianta, Yue-Wei Guo, Margherita Gavagnin |
| Source: |
Marine Drugs, Vol 17, Iss 11, p 603 (2019) |
| Publisher Information: |
MDPI AG, 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:Biology (General) |
| Subject Terms: |
nudibranch mollusks, isonitrile diterpenes, stereochemistry, ecological activity, Biology (General), QH301-705.5 |
| More Details: |
Terpene content of two distinct collections of the nudibranch Phyllidia coelestis from the South China Sea has been chemically analyzed. A series of amphilectene diterpenes, most likely of dietary origin, with isocyano and formamido functionalities have been isolated from both collections and spectroscopically characterized by an exhaustive nuclear magnetic resonance (NMR) analysis. Interestingly, the structural architecture of compounds 5−7 and 9 with both 8,13-cis and 12,13-cis ring junctions is unprecedented in the amphilectene skeleton. Metabolite 3, which was the most abundant in the nudibranch’s mantle, has been shown to deter feeding by a generalist predator, supporting its involvement in chemical defense. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1660-3397 |
| Relation: |
https://www.mdpi.com/1660-3397/17/11/603; https://doaj.org/toc/1660-3397 |
| DOI: |
10.3390/md17110603 |
| Access URL: |
https://doaj.org/article/41a23e5c46b34fe084b50b20e4c48d38 |
| Accession Number: |
edsdoj.41a23e5c46b34fe084b50b20e4c48d38 |
| Database: |
Directory of Open Access Journals |
