Bibliographic Details
| Title: |
Manipulations of phenylnorbornyl palladium species for multicomponent construction of a bridged polycyclic privileged scaffold |
| Authors: |
Lina Yin, Ting Guan, Jie Cheng, Dongchao Pan, Jinyang Lu, Jiahui Huang, Jiaqi Wu, Xiaoli Chen, Taiyun You, Xuting Huo, Yuting He, Jiayun Pang, Qingzhong Hu |
| Source: |
Communications Chemistry, Vol 5, Iss 1, Pp 1-13 (2022) |
| Publisher Information: |
Nature Portfolio, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Chemistry |
| Subject Terms: |
Chemistry, QD1-999 |
| More Details: |
Hexahydromethanocarbazole is a bridged polycyclic scaffold present in drugs and photoactive organic materials, however the efficient synthesis of this scaffold remains challenging. Here, the authors develop a multicomponent reaction cascade via phenylnorbornyl palladium species to generate hexahydromethanocarbazole-based libraries with CYP11B1 inhibition activity. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2399-3669 |
| Relation: |
https://doaj.org/toc/2399-3669 |
| DOI: |
10.1038/s42004-022-00759-4 |
| Access URL: |
https://doaj.org/article/4186f73826e74bd288e1ae54f412d3b3 |
| Accession Number: |
edsdoj.4186f73826e74bd288e1ae54f412d3b3 |
| Database: |
Directory of Open Access Journals |
