Sternal wound infection caused by Mycoplasma hominis in an adult patient: a case report and literature review

Bibliographic Details
Title: Sternal wound infection caused by Mycoplasma hominis in an adult patient: a case report and literature review
Authors: Shuang Li, Lili Yang, Yuanbiao Guo, Xiaoyan Feng, Ling Ye, Ke Li
Source: BMC Infectious Diseases, Vol 25, Iss 1, Pp 1-9 (2025)
Publisher Information: BMC, 2025.
Publication Year: 2025
Collection: LCC:Infectious and parasitic diseases
Subject Terms: Mycoplasma hominis, Postoperative infection, Sternal wound infection, Case report, Infectious and parasitic diseases, RC109-216
More Details: Abstract Background Mycoplasma hominis is a part of the microflora of the urogenital tract; however, extra-urogenital infections due to M. hominis are rare. Herein, we present a case study of a patient who successfully recovered from a sternal wound infection caused by M. hominis. Case presentation We report a case of sternal wound infection caused by M. hominis following tricuspid valvuloplasty. The patient developed a severe infection despite postoperative antimicrobial therapy. Wound sample cultures grew pinpoint-sized colonies on blood agar plates, which were identified as M. hominis by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Based on the results of the antibiotic susceptibility test, effective infection management was achieved using a combination of moxifloxacin and doxycycline. Conclusions The potential role of M. hominis as a causative agent of postoperative infections after thoracotomy may be underestimated. M. hominis should be highly suspected when patients have an indwelling catheter or when perioperative wound samples show numerous leukocytes with no visible bacteria, and are unresponsive to standard empirical treatment for postoperative infections.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1471-2334
Relation: https://doaj.org/toc/1471-2334
DOI: 10.1186/s12879-025-10607-0
Access URL: https://doaj.org/article/406601d0e33d403aa12dbf951b98ec94
Accession Number: edsdoj.406601d0e33d403aa12dbf951b98ec94
Database: Directory of Open Access Journals
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More Details
ISSN:14712334
DOI:10.1186/s12879-025-10607-0
Published in:BMC Infectious Diseases
Language:English