Academic Journal
Noninvasive evaluation of the hemodynamic status in patients after heart transplantation or left ventricular assist device implantation.
| Title: | Noninvasive evaluation of the hemodynamic status in patients after heart transplantation or left ventricular assist device implantation. |
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| Authors: | Sebastian Roth, Henrik Fox, René M'Pembele, Michiel Morshuis, Giovanna Lurati Buse, Markus W Hollmann, Ragnar Huhn, Thomas Bitter |
| Source: | PLoS ONE, Vol 17, Iss 10, p e0275977 (2022) |
| Publisher Information: | Public Library of Science (PLoS), 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Medicine LCC:Science |
| Subject Terms: | Medicine, Science |
| More Details: | IntroductionHemodynamic assessment is crucial after heart transplantation (HTX) or left ventricular assist device (LVAD) implantation. Gold-standard is invasive assessment via thermodilution (TD). Noninvasive pulse contour analysis (NPCA) is a new technology that is supposed to determine hemodynamics completely noninvasive. We aimed to validate this technology in HTX and LVAD patients and conducted a prospective single-center cohort study.MethodsPatients after HTX or LVAD implantation underwent right heart catheterization including TD. NPCA using the CNAP Monitor (V.5.2.14; CNSystems Medizintechnik AG, Graz, Austria) was performed simultaneously. Three TD measurements were compared with simultaneous NPCA measurements for hemodynamic assessment. To describe the agreement between TD and NPCA, Bland-Altman analysis was done.ResultsIn total, 28 patients were prospectively enrolled (HTX: n = 10, LVAD: n = 18). Bland-Altman analysis revealed a mean bias of +1.05 l/min (limits of agreement ± 4.09 l/min, percentage error 62.1%) for cardiac output (CO). In LVAD patients, no adequate NPCA signal could be obtained. In 5 patients (27.8%), any NPCA signal could be detected, but was considered as low signal quality.ConclusionIn conclusion, according to our limited data in a small cohort of HTX and LVAD patients, NPCA using the CNAP Monitor seems not to be suitable for noninvasive evaluation of the hemodynamic status. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1932-6203 |
| Relation: | https://doaj.org/toc/1932-6203 |
| DOI: | 10.1371/journal.pone.0275977 |
| Access URL: | https://doaj.org/article/400c1279ffae43fa85ff92abd588cc0d |
| Accession Number: | edsdoj.400c1279ffae43fa85ff92abd588cc0d |
| Database: | Directory of Open Access Journals |
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| ISSN: | 19326203 |
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| DOI: | 10.1371/journal.pone.0275977 |
| Published in: | PLoS ONE |
| Language: | English |