30-Day Mortality Following Palliative Radiotherapy

Bibliographic Details
Title: 30-Day Mortality Following Palliative Radiotherapy
Authors: Miriam Vázquez, Manuel Altabas, Diana C. Moreno, Abraham A. Geng, Santiago Pérez-Hoyos, Jordi Giralt
Source: Frontiers in Oncology, Vol 11 (2021)
Publisher Information: Frontiers Media S.A., 2021.
Publication Year: 2021
Collection: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Subject Terms: 30-day mortality, palliative radiation, end-of-life, prognosis, clinical indicator, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
More Details: Purpose30-day mortality (30-DM) is a parameter with widespread use as an indicator of avoidance of harm used in medicine. Our objective is to determine the 30-DM followed by palliative radiation therapy (RT) in our department and to identify potential prognosis factors.Material/MethodsWe conducted a retrospective cohort study including patients treated with palliative RT in our center during 2018 and 2019. Data related to clinical and treatment characteristics were collected.ResultsWe treated 708 patients to whom 992 palliative irradiations were delivered. The most frequent primary tumor sites were lung (31%), breast (14.8%), and gastrointestinal (14.8%). Bone was the predominant location of the treatment (56%), and the use of single doses was the preferred treatment schedule (34.4%). The 30-DM was 17.5%. For those who died in the first month the median survival was 17 days. Factors with a significant impact on 30-DM were: male gender (p < 0.0001); Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) of 2–3 (p = 0.0001); visceral metastases (p = 0.0353); lung, gastrointestinal or urinary tract primary tumors (p = 0.016); and single dose RT (p =
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2234-943X
Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.668481/full; https://doaj.org/toc/2234-943X
DOI: 10.3389/fonc.2021.668481
Access URL: https://doaj.org/article/a4008d0a10bd4c58abfb978b90f39c67
Accession Number: edsdoj.4008d0a10bd4c58abfb978b90f39c67
Database: Directory of Open Access Journals
More Details
ISSN:2234943X
DOI:10.3389/fonc.2021.668481
Published in:Frontiers in Oncology
Language:English