Association between Dental and Cardiovascular Diseases: A Systematic Review

Bibliographic Details
Title: Association between Dental and Cardiovascular Diseases: A Systematic Review
Authors: Louis Hardan, Anthony Matta, Rim Bourgi, Carlos Enrique Cuevas-Suárez, Walter Devoto, Maciej Zarow, Natalia Jakubowicz, Francisco Campelo-Parada, Meyer Elbaz, Didier Carrié, Jerome Roncalli
Source: Reviews in Cardiovascular Medicine, Vol 24, Iss 6, p 159 (2023)
Publisher Information: IMR Press, 2023.
Publication Year: 2023
Collection: LCC:Diseases of the circulatory (Cardiovascular) system
Subject Terms: cardiovascular disease, clinical trials, dental, infection, tooth disease, Diseases of the circulatory (Cardiovascular) system, RC666-701
More Details: Background: The link between dental, infective and obstructive cardiovascular diseases is debatable. Aim: To systematically review the literature to assess the association between dental conditions and development of cardiovascular disease. Methods: The systematic review was conducted following the PRISMA guidelines using PubMed (Medline), Web of Science, Scopus, EMBASE and SciELO. Results: Out of 6680 records, 82 articles were eligible for inclusion after reviewing titles and abstracts. No association between dental disease and cardiovascular disease has been observed in 10 studies while a potential link has been suggested by the remaining trials. Tooth loss and periodontitis are the main evaluated oral conditions while coronary artery disease, stroke, atherosclerosis and myocardial infarction represent the major cardiovascular events. The interaction between these two clinical entities is based on direct mechanism mediated by systemic inflammatory response, leakage of cytokines and endothelial cells invasion by oral pathogens and indirect mechanism mediated by common risk factors or confounders. Conclusions: It seems that tooth loss, periodontitis and poor oral hygiene increase the risk of atherosclerotic cardiovascular events, and subsequently oral health care professionals could contribute to public health cardiovascular control efforts.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1530-6550
Relation: https://www.imrpress.com/journal/RCM/24/6/10.31083/j.rcm2406159; https://doaj.org/toc/1530-6550
DOI: 10.31083/j.rcm2406159
Access URL: https://doaj.org/article/3e97c52b42854366b08120df162de30d
Accession Number: edsdoj.3e97c52b42854366b08120df162de30d
Database: Directory of Open Access Journals
More Details
ISSN:15306550
DOI:10.31083/j.rcm2406159
Published in:Reviews in Cardiovascular Medicine
Language:English