Bibliographic Details
| Title: |
A Case of Glucocorticoid Hypersensitivity Syndrome Associated With Underlying Rubella Virus Infection |
| Authors: |
Zhen Zhang, MS, Ying Feng, PhD, Yang Cao, PhD, Yan Chen, MS, Fangping Li, PhD |
| Source: |
AACE Clinical Case Reports, Vol 7, Iss 6, Pp 367-371 (2021) |
| Publisher Information: |
Elsevier, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Diseases of the endocrine glands. Clinical endocrinology |
| Subject Terms: |
Cushing syndrome, glucocorticoid hypersensitivity, hypocortisolemia, rubella virus, case report, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| More Details: |
Objective: The objective of this article is to report a rare case of glucocorticoid hypersensitivity syndrome, which may be associated with an underlying rubella virus infection. Case Report: A 29-year-old man showed progressive weight gain for 16 months accompanied by a moon face, enlarged dorsocervical fat pad, central obesity, and purple striae. His cortisol circadian rhythm was normal, and plasma cortisol levels at 8:00 AM fluctuated between 3.2 and 9.54 μg/dL (reference range, 4.3-22.4 μg/dL). A dexamethasone suppression test with a very low dose (0.25 mg) of dexamethasone showed a marked decrease in plasma cortisol level to 0 μg/dL. Adrenal computed tomography and pituitary magnetic resonance imaging findings were normal. The Z-score of the bone density in the lumbar spine was −4.2. The IgM antibody for the rubella virus was positive. His erythrocyte sedimentation rate was 24 mm/hour (reference range, |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2376-0605 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2376060521000833; https://doaj.org/toc/2376-0605 |
| DOI: |
10.1016/j.aace.2021.06.010 |
| Access URL: |
https://doaj.org/article/3e055b517fd04b0793230b6caf394d69 |
| Accession Number: |
edsdoj.3e055b517fd04b0793230b6caf394d69 |
| Database: |
Directory of Open Access Journals |
