Opioid-free anesthesia with esketamine-dexmedetomidine versus opioid-based anesthesia with propofol-remifentanil in shoulder arthroscopy: a randomized controlled trial

Bibliographic Details
Title: Opioid-free anesthesia with esketamine-dexmedetomidine versus opioid-based anesthesia with propofol-remifentanil in shoulder arthroscopy: a randomized controlled trial
Authors: Zhouya Xue, Cong Yan, Yi Liu, Nan Yang, Geqing Zhang, Weisheng Qian, Bin Qian, Xiang Liu
Source: BMC Surgery, Vol 24, Iss 1, Pp 1-10 (2024)
Publisher Information: BMC, 2024.
Publication Year: 2024
Collection: LCC:Surgery
Subject Terms: Opioid-free anesthesia, Esketamine, Dexmedetomidine, Shoulder arthroscopy, Surgery, RD1-811
More Details: Abstract Background OFA (Opioid-free anesthesia) has the potential to reduce the occurrence of opioid-related adverse events and enhance postoperative recovery. Our research aimed to investigate whether OFA, combining esketamine and dexmedetomidine, could serve as an alternative protocol to traditional OBA (opioid-based anesthesia) in shoulder arthroscopy, particularly in terms of reducing PONV (postoperative nausea and vomiting). Methods A total of 60 patients treated with shoulder arthroscopy from September 2021 to September 2022 were recruited. Patients were randomly assigned to the OBA group (n = 30) and OFA group (n = 30), receiving propofol-remifentanil TIVA (total intravenous anesthesia) and esketamine-dexmedetomidine intravenous anesthesia, respectively. Both groups received ultrasound-guided ISBPB(interscalene brachial plexus block)for postoperative analgesia. Results The incidence of PONV on the first postoperative day in the ward (13.3% vs. 40%, P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1471-2482
Relation: https://doaj.org/toc/1471-2482
DOI: 10.1186/s12893-024-02518-9
Access URL: https://doaj.org/article/3dec78e2eeda468a97434fd10d9fb40f
Accession Number: edsdoj.3dec78e2eeda468a97434fd10d9fb40f
Database: Directory of Open Access Journals
More Details
ISSN:14712482
DOI:10.1186/s12893-024-02518-9
Published in:BMC Surgery
Language:English