Burden of varicella in the Asia-Pacific region: a systematic literature review
| Title: | Burden of varicella in the Asia-Pacific region: a systematic literature review |
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| Authors: | Anne Eng Neo Goh, Eun Hwa Choi, Kulkanya Chokephaibulkit, Jaydeep Choudhury, Barbara Kuter, Ping-Ing Lee, Helen Marshall, Jin Oh Kim, Lara J. Wolfson |
| Source: | Expert Review of Vaccines, Vol 18, Iss 5, Pp 475-493 (2019) |
| Publisher Information: | Taylor & Francis Group, 2019. |
| Publication Year: | 2019 |
| Collection: | LCC:Internal medicine |
| Subject Terms: | disease burden, epidemiology, national immunization program, vaccine, varicella, Internal medicine, RC31-1245 |
| More Details: | Introduction: Varicella is a highly contagious infection that can lead to serious complications, particularly in high-risk groups; however, it is vaccine preventable. Disease awareness and understanding of the disease burden can strongly influence vaccine coverage. This review provides insight into the current epidemiology and the importance of varicella from both public health and economic perspectives across the Asia-Pacific (APAC) region. Areas covered: A systematic literature review was conducted to identify studies on the incidence, seroprevalence, fatality rate and complication rate of varicella. Economic burden studies were also captured. Altogether, 125 studies were identified across the region; these were supplemented by government reports (gray data). Reported vaccine coverage varied from 2.8% to 97%; a key influencing factor was inclusion of the varicella vaccine in national immunization programs. In general, varicella incidence in the unvaccinated population was highest in children ≤5 years old and seroprevalence increased with age. Economic analyses highlighted the cost-saving potential of vaccination programs, especially from a societal perspective. Expert opinion: Varicella-related data varied greatly across the APAC region, highlighting the need to better understand the burden of varicella in this area, and particularly identified the need for better surveillance and reporting. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1476-0584 1744-8395 14760584 |
| Relation: | https://doaj.org/toc/1476-0584; https://doaj.org/toc/1744-8395 |
| DOI: | 10.1080/14760584.2019.1594781 |
| Access URL: | https://doaj.org/article/3ddb3bf3b999472fbab90b0885b031b3 |
| Accession Number: | edsdoj.3ddb3bf3b999472fbab90b0885b031b3 |
| Database: | Directory of Open Access Journals |
| ISSN: | 14760584 17448395 |
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| DOI: | 10.1080/14760584.2019.1594781 |
| Published in: | Expert Review of Vaccines |
| Language: | English |