Bibliographic Details
| Title: |
Scanning Tunneling Microscopy Study of Lipoic Acid, Mannose, and cRGD@AuNPs Conjugates |
| Authors: |
Andrés Rodríguez-Galván, Mitzi Reyes, Marisol Ávila-Cruz, Margarita Rivera, Vladimir A. Basiuk |
| Source: |
Nanomaterials, Vol 13, Iss 18, p 2596 (2023) |
| Publisher Information: |
MDPI AG, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Chemistry |
| Subject Terms: |
biofunctionalization, gold nanoparticles, lipoic acid, mannose, RGD cyclic peptide, scanning tunneling microscopy, Chemistry, QD1-999 |
| More Details: |
The functionalization of AuNPs with different biological elements was achieved to investigate their possibility in biomedical applications such as drug delivery, vaccine development, sensing, and imaging. Biofunctionalized AuNPs are pursued for applications such as drug delivery, vaccine development, sensing, and imaging. In this study, AuNPs with diameters of 20 nm were functionalized with lipoic acid, mannose, or the cRGD peptide. By using UV-vis spectroscopy, Fourier transform infrared spectroscopy, dynamic light scattering, transmission electron microscopy, and scanning tunneling microscopy techniques, we showed that AuNPs can be functionalized by these biomolecules in a reliable way to obtain conjugates to explore potential biomedical applications. In particular, we demonstrate that the STM technique can be employed to analyze biofunctionalized AuNPs, and the obtained information can be valuable in the design of biomedical applications. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2079-4991 |
| Relation: |
https://www.mdpi.com/2079-4991/13/18/2596; https://doaj.org/toc/2079-4991 |
| DOI: |
10.3390/nano13182596 |
| Access URL: |
https://doaj.org/article/d3c3eca64ad146a9aa849896694cc1e2 |
| Accession Number: |
edsdoj.3c3eca64ad146a9aa849896694cc1e2 |
| Database: |
Directory of Open Access Journals |
