Videodensitometric Methods for Cardiac Output Measurements

Bibliographic Details
Title: Videodensitometric Methods for Cardiac Output Measurements
Authors: Massimo Mischi, Erik Korsten, Ton Kalker
Source: EURASIP Journal on Advances in Signal Processing, Vol 2003, Iss 5, Pp 479-489 (2003)
Publisher Information: SpringerOpen, 2003.
Publication Year: 2003
Collection: LCC:Telecommunication
LCC:Electronics
Subject Terms: contrast agents, local density random walk, ultrasound, videodensitometry., Telecommunication, TK5101-6720, Electronics, TK7800-8360
More Details: Cardiac output is often measured by indicator dilution techniques, usually based on dye or cold saline injections. Developments of more stable ultrasound contrast agents (UCA) are leading to new noninvasive indicator dilution methods. However, several problems concerning the interpretation of dilution curves as detected by ultrasound transducers have arisen. This paper presents a method for blood flow measurements based on UCA dilution. Dilution curves are determined by real-time densitometric analysis of the video output of an ultrasound scanner and are automatically fitted by the Local Density Random Walk model. A new fitting algorithm based on multiple linear regression is developed. Calibration, that is, the relation between videodensity and UCA concentration, is modelled by in vitro experimentation. The flow measurement system is validated by in vitro perfusion of SonoVue contrast agent. The results show an accurate dilution curve fit and flow estimation with determination coefficient larger than 0.95 and 0.99, respectively.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 16876172
1687-6172
1687-6180
Relation: https://doaj.org/toc/1687-6172; https://doaj.org/toc/1687-6180
DOI: 10.1155/S1110865703211185
DOI: 10.1155/S1687617203211185
Access URL: https://doaj.org/article/3b8d50bb76f447b38eeb3fb2f6c46cc3
Accession Number: edsdoj.3b8d50bb76f447b38eeb3fb2f6c46cc3
Database: Directory of Open Access Journals
More Details
ISSN:16876172
16876180
DOI:10.1155/S1110865703211185
Published in:EURASIP Journal on Advances in Signal Processing
Language:English