Bibliographic Details
| Title: |
Cardiovascular risk factors and the impact on prognosis in patients with chronic kidney disease secondary to autosomal dominant polycystic kidney disease |
| Authors: |
José Luis Gorriz, David Arroyo, Luis D’Marco, Roser Torra, Patricia Tomás, María Jesús Puchades, Nayara Panizo, Jonay Pantoja, Marco Montomoli, José Luis Llisterri, Vicente Pallares-Carratalá, José Manuel Valdivielso |
| Source: |
BMC Nephrology, Vol 22, Iss 1, Pp 1-10 (2021) |
| Publisher Information: |
BMC, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Diseases of the genitourinary system. Urology |
| Subject Terms: |
Autosomal dominant polycystic kidney disease, Chronic kidney disease, Cardiovascular disease, Nephropathy, Diseases of the genitourinary system. Urology, RC870-923 |
| More Details: |
Abstract Background Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent hereditary renal disease. There is an increased rate of cardiovascular disease (CVD) in ADPKD. In this study, we evaluate the prevalence of cardiovascular risk factors, the achievement rates for treatment goals and cardiovascular events (CVE) in ADPKD and their relations with asymptomatic CVD in CKD from other etiologies (CKDoe) and controls. Methods We evaluated 2445 CKD patients (2010–2012). The information collected was: clinical, anthropometric and analytical parameters, treatments and CVD evaluation (intima-media thickness (IMT), atheromatous plaque presence and ankle-brachial index (ABI)). Laboratory, vital status, CVE and hospitalizations were collected for 4 years. Results ADPKD patients had a worse renal function and worst achievement of blood pressure, higher parathormone levels but lower proteinuria compared to CKDoe. ADPKD patients presented lower IMT values than other groups, however, an intermediate rate of pathologic ABI and atheromatous plaque was present. More than half of the patients received statins, achieving LDL-c levels |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2369 |
| Relation: |
https://doaj.org/toc/1471-2369 |
| DOI: |
10.1186/s12882-021-02313-1 |
| Access URL: |
https://doaj.org/article/3b293d07ef4a48f4bf8ab36ab7825a1f |
| Accession Number: |
edsdoj.3b293d07ef4a48f4bf8ab36ab7825a1f |
| Database: |
Directory of Open Access Journals |
