Bibliographic Details
| Title: |
Evaluation of Rapid Antigen Test Results and Real-time Reverse Transcription Polymerase Chain Reaction for the Laboratory Diagnosis of SARS-CoV-2 |
| Authors: |
Yeliz TANRIVERDİ ÇAYCI, Zeliha SEYFİ, Kübra HACIEMİNOĞLU ÜLKER, Demet GÜR VURAL, Kemal BİLGİN, Hızır Ufuk AKDEMİR, Esra AKYÜZ ÖZKAN, Asuman BİRİNCİ |
| Source: |
Mediterranean Journal of Infection, Microbes and Antimicrobials, Vol 12, Iss 1 (2023) |
| Publisher Information: |
Galenos Yayinevi, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Medicine
LCC:Infectious and parasitic diseases |
| Subject Terms: |
sars-cov-2, antigen test, covid-19, Medicine, Infectious and parasitic diseases, RC109-216 |
| More Details: |
Introduction: Real-time reverse transcription-polymerase chain reaction (RT-PCR) is the gold standard method for the diagnosis of Severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) infection. However, real-time RT-PCR is time-consuming, expensive, and requires special laboratory conditions and experienced personnel. Thus, the diagnostic importance of faster and easier-to-perform antigen-detecting rapid diagnostic tests (Ag-RDTs) has increased. With on-site application and fast turnaround time, Ag-RDTs provide quick isolation, minimizing the risk of transmission. We aimed to compare the results of the Mö-Screen Corona Antigen Test (MöLab, Langenfeld, Germany) and real-time RT-PCR. Materials and Methods: Nasopharyngeal swabs from 863 patients from January 2022 to March 2022 were included in the study. The SARS-CoV-2 antigen was assessed for using the Mö-Screen Corona Antigen Test. The SARS-CoV-2 real-time RT-PCR results were obtained within two days in 417 patients. Results: The agreeability of the real-time RT-PCR and Ag-RDT results was 96.2%. The sensitivity and specificity of Ag-RDT were 84.8% and 100%, respectively. The test sensitivity increased to 92% in specimens with Ct value |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
Turkish |
| ISSN: |
2147-673X |
| Relation: |
https://mjima.org/text.php?&id=378; https://doaj.org/toc/2147-673X |
| DOI: |
10.4274/mjima.galenos.2023.2023.12 |
| Access URL: |
https://doaj.org/article/3ab9cf3779464f83a0188eb88468c5e3 |
| Accession Number: |
edsdoj.3ab9cf3779464f83a0188eb88468c5e3 |
| Database: |
Directory of Open Access Journals |
