Bibliographic Details
| Title: |
Ameliorative effect of liprotide-encapsulated vitamin D3 on blood glucose, calcium homeostasis, and vitamin D level in a vitamin D and calcium deficient rat model |
| Authors: |
Gemala Anjani, Reza Achmad Maulana, Sylvia Rahmi Putri, Faizah Fulyani, Ahmad Syauqy, Diana Nur Afifah, Fitriyono Ayustaningwarno, Refani Alycia Kusuma, Zulfatul Masruroh |
| Source: |
Frontiers in Nutrition, Vol 12 (2025) |
| Publisher Information: |
Frontiers Media S.A., 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Nutrition. Foods and food supply |
| Subject Terms: |
encapsulation, blood glucose, calcium, liprotide, vitamin D3, Nutrition. Foods and food supply, TX341-641 |
| More Details: |
Vitamin D3, recognized for its higher bioavailability and direct cell utilization, plays a vital role in the human body. Applying β-lactoglobulin with oleic acid (β-Lg-AO) as an encapsulating agent is anticipated to protect and enhance the transport of vitamin D3 to the gastrointestinal system. This study aimed to evaluate effect of liprotide-encapsulated vitamin D3 in a vitamin D-deficient rat on blood glucose, Vitamin D and calcium status. This is pre-post intervention. 24 mice were divided into 4 groups: (K-) normal rats; (K+) rat model of vitamin D and calcium deficiency; (P1) rat model of vitamin D and calcium deficiency with vitamin D3 intervention; (P2) rat model of vitamin D and calcium deficiency with liprotide-encapsulated vitamin D3 intervention. The administered dose of vitamin D3 was 180 IU (2 mL solution). Liprotide-encapsulated vitamin D3 intervention in vitamin D and calcium deficiency rats can significantly increase vitamin D (25 (OH)D) and calcium levels (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2296-861X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fnut.2025.1514179/full; https://doaj.org/toc/2296-861X |
| DOI: |
10.3389/fnut.2025.1514179 |
| Access URL: |
https://doaj.org/article/3a0af551ca3a4d109467428ab996e27a |
| Accession Number: |
edsdoj.3a0af551ca3a4d109467428ab996e27a |
| Database: |
Directory of Open Access Journals |
