Bibliographic Details
| Title: |
Characteristics and mechanical mechanisms of intervertebral disc degeneration in old thoracolumbar fractures with kyphosis: clinical observations and finite element analyses |
| Authors: |
Xi-long Cui, Wan-mei Yang, Ao Ding, Junjun Zhu, Wei Zhang, Hao Wu, Ji-shi Jiang, Yun-lei Zhai, Hai-yang Yu, Zi-kai Hua |
| Source: |
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-14 (2024) |
| Publisher Information: |
BMC, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Diseases of the musculoskeletal system |
| Subject Terms: |
Old thoracolumbar fractures, Kyphosis, Intervertebral disc degeneration, Intervertebral disc pressure, Finite element analysis, Diseases of the musculoskeletal system, RC925-935 |
| More Details: |
Abstract Background Low back pain is a common complication in patients with old thoracolumbar fractures with kyphosis (OTLFK), and intervertebral disc degeneration (IDD) is a major contributor. Mechanical abnormalities are believed to play a key role in the development to IDD. This study aimed to investigate the characteristics of lumbar disc degeneration and underlying mechanical mechanisms in patients with OTLFK. Methods A total of 52 patients with OTLFK were included from February 2017 to March 2023 as the observation group (OG). A control group (CG) of individuals with chronic low back pain were matched for age, body mass index, and gender. The disc degeneration grades and distribution in both groups were observed. Intact, 20°, 30°, and 40° kyphotic finite element (FE) models were established. Intervertebral disc pressures (IDPs) were calculated under standing, flexion, extension, lateral bending, and axial rotation conditions. Results The overall IDD in the OG was higher than that in the CG. The grades from T11 to L3 were higher in the OG (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2474 |
| Relation: |
https://doaj.org/toc/1471-2474 |
| DOI: |
10.1186/s12891-024-08157-8 |
| Access URL: |
https://doaj.org/article/39f7574994b946adb9f1ba21cd3fc397 |
| Accession Number: |
edsdoj.39f7574994b946adb9f1ba21cd3fc397 |
| Database: |
Directory of Open Access Journals |
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