Academic Journal
Estimated pulse wave velocity improves risk stratification for all-cause mortality in patients with COVID-19
| Title: | Estimated pulse wave velocity improves risk stratification for all-cause mortality in patients with COVID-19 |
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| Authors: | Kimon Stamatelopoulos, Georgios Georgiopoulos, Kenneth F. Baker, Giusy Tiseo, Dimitrios Delialis, Charalampos Lazaridis, Greta Barbieri, Stefano Masi, Nikolaos I. Vlachogiannis, Kateryna Sopova, Alessandro Mengozzi, Lorenzo Ghiadoni, Ina Schim van der Loeff, Aidan T. Hanrath, Bajram Ajdini, Charalambos Vlachopoulos, Meletios A. Dimopoulos, Christopher J. A. Duncan, Marco Falcone, Konstantinos Stellos, the Pisa COVID-19 Research Group, Newcastle COVID-19 Research Group |
| Source: | Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021) |
| Publisher Information: | Nature Portfolio, 2021. |
| Publication Year: | 2021 |
| Collection: | LCC:Medicine LCC:Science |
| Subject Terms: | Medicine, Science |
| More Details: | Abstract Accurate risk stratification in COVID-19 patients consists a major clinical need to guide therapeutic strategies. We sought to evaluate the prognostic role of estimated pulse wave velocity (ePWV), a marker of arterial stiffness which reflects overall arterial integrity and aging, in risk stratification of hospitalized patients with COVID-19. This retrospective, longitudinal cohort study, analyzed a total population of 1671 subjects consisting of 737 hospitalized COVID-19 patients consecutively recruited from two tertiary centers (Newcastle cohort: n = 471 and Pisa cohort: n = 266) and a non-COVID control cohort (n = 934). Arterial stiffness was calculated using validated formulae for ePWV. ePWV progressively increased across the control group, COVID-19 survivors and deceased patients (adjusted mean increase per group 1.89 m/s, P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-021-99050-0 |
| Access URL: | https://doaj.org/article/ded39e867e484e78b934fe776c94ca42 |
| Accession Number: | edsdoj.39e867e484e78b934fe776c94ca42 |
| Database: | Directory of Open Access Journals |
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| ISSN: | 20452322 |
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| DOI: | 10.1038/s41598-021-99050-0 |
| Published in: | Scientific Reports |
| Language: | English |